Literature DB >> 6153696

Dichotomy between the induction of suppressor cells and immunologic tolerance by adult thymectomy.

Y Borel, L Kilham, S E Kurtz, C L Reinisch.   

Abstract

Adult thymectomy prevents the development of suppressor T cells without impairing the induction of immunologic tolerance to the same antigenic determinant. This finding demonstrates that the cellular mechanisms underlying immune suppression and immune tolerance are different.

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Year:  1980        PMID： 6153696      PMCID： PMC2185794          DOI： 10.1084/jem.151.3.743

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  18 in total

Review 1.  The role of specific suppressor T cells in immune tolerance.

Authors:  D Nachtigal; I Zan-Bar; M Feldman
Journal:  Transplant Rev       Date:  1975

2.  Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy.

Authors:  J W Kappler; P C Hunter; D Jacobs; E Lord
Journal:  J Immunol       Date:  1974-07       Impact factor: 5.422

3.  The tolerant cell: direct evidence for receptor blockade by tolerogen.

Authors:  M Aldo-Benson; Y Borel
Journal:  J Immunol       Date:  1974-05       Impact factor: 5.422

4.  Role of the thymus in tolerance. X. "Suppressor" activity of antigen-stimulated rat thymocytes transferred to normal recipients.

Authors:  T Y Ha; B H Waksman
Journal:  J Immunol       Date:  1973-05       Impact factor: 5.422

5.  Delayed effect of thymectomy in adult life on immunological competence.

Authors:  D Metcalf
Journal:  Nature       Date:  1965-12-25       Impact factor: 49.962

6.  Nucleoside specificity in the carrier IgG-dependent induction of tolerance.

Authors:  B D Stollar; Y Borel
Journal:  J Immunol       Date:  1976-10       Impact factor: 5.422

7.  T and B cell in hapten-specific carrier-determined tolerance.

Authors:  Y Borel; C L Reinisch; S F Schlossman
Journal:  J Exp Med       Date:  1975-11-01       Impact factor: 14.307

8.  Regulation of cytotoxic T-cell reactivity to syngeneic tumors by the thymus.

Authors:  C L Reinisch; S L Andrew
Journal:  J Exp Med       Date:  1978-08-01       Impact factor: 14.307

9.  Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice.

Authors:  H Cantor; L McVay-Boudreau; J Hugenberger; K Naidorf; F W Shen; R K Gershon
Journal:  J Exp Med       Date:  1978-04-01       Impact factor: 14.307

10.  Induction and mode of action of suppressor cells generated against human gamma globulin. I. An immunologic unresponsive state devoid of demonstrable suppressor cells.

Authors:  D E Parks; M V Doyle; W O Weigle
Journal:  J Exp Med       Date:  1978-09-01       Impact factor: 14.307
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  6 in total

Review 1.  From nonspecific to specific immunosuppression: facts and speculation.

Authors:  Y Borel
Journal:  Springer Semin Immunopathol       Date:  1984

2.  Atrophy of the thymic cortex in mice with granulomatous schistosomiasis mansoni.

Authors:  S R Wellhausen; D L Boros
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

3.  Temporal changes of suppressor T lymphocytes and cytotoxic T lymphocytes in syngeneic murine malignant gliomas.

Authors:  T Yamasaki; H Handa; J Yamashita; Y Namba; M Hanaoka
Journal:  J Neurooncol       Date:  1986       Impact factor: 4.130

4.  Strain-dependent protective effect of adult thymectomy on murine infection by Mycobacterium lepraemurium.

Authors:  M A Bach; A Hoffenbach
Journal:  Clin Exp Immunol       Date:  1987-06       Impact factor: 4.330

5.  Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.

Authors:  Pascal Schlosser; Yong Li; Peggy Sekula; Johannes Raffler; Franziska Grundner-Culemann; Maik Pietzner; Yurong Cheng; Matthias Wuttke; Inga Steinbrenner; Ulla T Schultheiss; Fruzsina Kotsis; Tim Kacprowski; Lukas Forer; Birgit Hausknecht; Arif B Ekici; Matthias Nauck; Uwe Völker; Gerd Walz; Peter J Oefner; Florian Kronenberg; Robert P Mohney; Michael Köttgen; Karsten Suhre; Kai-Uwe Eckardt; Gabi Kastenmüller; Anna Köttgen
Journal:  Nat Genet       Date:  2020-01-20       Impact factor: 38.330

6.  A natural model of immunologic tolerance. Tolerance to murine C5 is mediated by T cells, and antigen is required to maintain unresponsiveness.

Authors:  D E Harris; L Cairns; F S Rosen; Y Borel
Journal:  J Exp Med       Date:  1982-08-01       Impact factor: 14.307
  6 in total

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