Literature DB >> 6153132

Synthesis, transport, and release of posterior pituitary hormones.

M J Brownstein, J T Russell, H Gainer.   

Abstract

Vasopressin and oxytocin are made and released by neurons of the hypothalamo-neurohypophysial system. Pulse labeling these neurons with radioactive amino acid indicates that the two hormones and their respective neurophysin carrier proteins are synthesized as parts of separate precursor proteins. The precursors seem to be processed into smaller, biologically active molecules while they are being transported along the axon.

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Year:  1980        PMID: 6153132     DOI: 10.1126/science.6153132

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  152 in total

1.  Excitatory role of the hyperpolarization-activated inward current in phasic and tonic firing of rat supraoptic neurons.

Authors:  M Ghamari-Langroudi; C W Bourque
Journal:  J Neurosci       Date:  2000-07-01       Impact factor: 6.167

2.  Molecular modeling of the neurophysin I/oxytocin complex.

Authors:  R Kaźmierkiewicz; C Czaplewski; B Lammek; J Ciarkowski
Journal:  J Comput Aided Mol Des       Date:  1997-01       Impact factor: 3.686

Review 3.  Ovarian hormone action in the hypothalamic ventromedial nucleus: remodelling to regulate reproduction.

Authors:  G D Griffin; L M Flanagan-Cato
Journal:  J Neuroendocrinol       Date:  2011-06       Impact factor: 3.627

4.  Electrolytes in the aging.

Authors:  Lynn E Schlanger; James L Bailey; Jeff M Sands
Journal:  Adv Chronic Kidney Dis       Date:  2010-07       Impact factor: 3.620

5.  Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atom.

Authors:  L Q Chen; J P Rose; E Breslow; D Yang; W R Chang; W F Furey; M Sax; B C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

6.  Radioautographic study of glycoprotein synthesis and fate in the hypothalamo-neurohypophyseal system of vasopressin-deficient Brattleboro rats.

Authors:  A Haddad; G Pelletier
Journal:  Anat Embryol (Berl)       Date:  1987

Review 7.  Oxytocin Modulation of Neural Circuits.

Authors:  Mariela Mitre; Jessica Minder; Egzona X Morina; Moses V Chao; Robert C Froemke
Journal:  Curr Top Behav Neurosci       Date:  2018

8.  EGFP-tagged vasopressin precursor protein sorting into large dense core vesicles and secretion from PC12 cells.

Authors:  Bing-Jun Zhang; Mitsuo Yamashita; Ray Fields; Kiyoshi Kusano; Harold Gainer
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046

Review 9.  Dynamic alterations in luteinizing hormone-releasing hormone (LHRH) neuronal cell bodies and terminals of adult rats.

Authors:  J C King; B S Rubin
Journal:  Cell Mol Neurobiol       Date:  1995-02       Impact factor: 5.046

10.  Effects of tunicamycin on the hypothalamo-neurohypophysial system of the rat.

Authors:  C B González; R W Swann; B T Pickering
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

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