Literature DB >> 6152725

New steroids with antiprogestational and antiglucocorticoid activities.

G Neef, S Beier, W Elger, D Henderson, R Wiechert.   

Abstract

A number of 11-substituted 19-norsteroids with inverse configuration at C-13 were synthesized. 11 beta-Aryl compounds in this series were found to possess antiprogestational and antiglucocorticoid activities.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6152725     DOI： 10.1016/s0039-128x(84)80027-6

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  12 in total

1.  Changes in rat myometrial plasma membrane protein kinase A are confined to parturition.

Authors:  Chun-Ying Ku; Dilyara A Murtazina; Yoon-Sun Kim; Robert E Garfield; Barbara M Sanborn
Journal:  Reprod Sci       Date:  2010-05-10       Impact factor: 3.060

Review 2.  Myelin disorders: Causes and perspectives of Charcot-Marie-Tooth neuropathy.

Authors:  Gerd Meyer zu Hörste; Thomas Prukop; Klaus-Armin Nave; Michael W Sereda
Journal:  J Mol Neurosci       Date:  2006       Impact factor: 3.444

3.  Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells.

Authors:  L Klein-Hitpass; A C Cato; D Henderson; G U Ryffel
Journal:  Nucleic Acids Res       Date:  1991-03-25       Impact factor: 16.971

4.  In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA.

Authors:  K Delabre; A Guiochon-Mantel; E Milgrom
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-15       Impact factor: 11.205

5.  Selective effects of 8-Br-cAMP on agonists and antagonists of the glucocorticoid receptor.

Authors:  S Zhang; M Danielsen
Journal:  Endocrine       Date:  1995-01       Impact factor: 3.633

6.  Population pharmacokinetics of telapristone (CDB-4124) and its active monodemethylated metabolite CDB-4453, with a mixture model for total clearance.

Authors:  Denise Morris; Joseph Podolski; Alan Kirsch; Ronald Wiehle; Lawrence Fleckenstein
Journal:  AAPS J       Date:  2011-10-25       Impact factor: 4.009

7.  Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies.

Authors:  H Michna; M R Schneider; Y Nishino; M F el Etreby
Journal:  Breast Cancer Res Treat       Date:  1989-12       Impact factor: 4.872

8.  The tumour-inhibiting potential of the progesterone antagonist Onapristone in the human mammary carcinoma T61 in nude mice.

Authors:  M R Schneider; H Michna; U F Habenicht; Y Nishino; H J Grill; K Pollow
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

9.  The selective progesterone receptor modulator CDB4124 inhibits proliferation and induces apoptosis in uterine leiomyoma cells.

Authors:  Xia Luo; Ping Yin; John S Coon V; You-Hong Cheng; Ronald D Wiehle; Serdar E Bulun
Journal:  Fertil Steril       Date:  2010-01-08       Impact factor: 7.329

Review 10.  Antiprogestin pharmacodynamics, pharmacokinetics, and metabolism: implications for their long-term use.

Authors:  G R Jang; L Z Benet
Journal:  J Pharmacokinet Biopharm       Date:  1997-12
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.