Time controlled computed tomographic angiography.

A technique is described which, by exact timing of injection and computed tomography (CT) scans, allows a high contrast medium concentration in blood (14 mg iodine/ml blood) to be reached for a brief period, sufficient for a fast scan of 5 to 10 sec duration. This scan demonstrates the early perfusion of the vascular bed of the various organs. With serial, fast CT scans of the same section with 30 sec intervals for 3 min, a dynamic investigation of contrast medium distribution in vessels, tissue, and excretory pathways may be obtained. Preliminary experiments indicate the promising usefulness of this type of examination for brain, kidney, pancreas, spleen, liver, and small bowel.