Computer-assisted EEG topography as a tool in the evaluation of actions of psychoactive drugs in patients.

This paper summarizes a tentative application of EEG topography to the evaluation of the efficiency of psychoactive drugs. It shows that the spectral content of the EEG, recorded simultaneously at different locations according to the international 10-20 system, is a sensitive measure for the quantification of drug activity. Furthermore, coherence analysis reveals differences in the functional organization of the neocortex under neuroleptic drug therapy.