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Literature DB >> 6151851

Ambulatory motor activity monitoring to study the timecourse of hypnotic action.

Abstract

A solid state activity monitor worn on the wrist was used to study the effect of flunitrazepam, flurazepam, temazepam, triazolam and midazolam. All compounds reduced motor activity in the first half, but only flunitrazepam and flurazepam had an effect during the second half of the bed rest period. Ambulatory activity monitoring is an unobtrusive and simple method for investigating timecourse of action.

Entities: Chemical

Mesh：

Substances：

Year: 1984 PMID： 6151851 PMCID： PMC1463338 DOI： 10.1111/j.1365-2125.1984.tb02585.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

7 in total

1. Melancholia and barbiturates: a controlled EEG, body and eye movement study of sleep.

Authors: I OSWALD; R J BERGER; R A JARAMILLO; K M KEDDIE; P C OLLEY; G B PLUNKETT
Journal: Br J Psychiatry Date: 1963-01 Impact factor: 9.319

2. Hypnotic action and residual effects of a single bedtime dose of temazepam.

Authors: A A Borbély; P Mattmann; M Loepfe
Journal: Arzneimittelforschung Date: 1984

3. A single dose of benzodiazepine hypnotics alters the sleep EEG in the subsequent drug-free night.

Authors: A A Borbély; P Mattmann; M Loepfe; I Fellmann; M Gerne; I Strauch; D Lehmann
Journal: Eur J Pharmacol Date: 1983-04-22 Impact factor: 4.432

4. Automated gas chromatography for studies of midazolam pharmacokinetics.

Authors: D J Greenblatt; A Locniskar; H R Ochs; P M Lauven
Journal: Anesthesiology Date: 1981-08 Impact factor: 7.892

5. [Long term recording of motor activity: its use in research and clinical situations].

Authors: A A Borbély; H U Neuhaus; P Mattmann; P G Waser
Journal: Schweiz Med Wochenschr Date: 1981-05-23

6. Midazolam and triazolam: hypnotic action and residual effects after a single bedtime dose.

Authors: A A Borbély; M Loepfe; P Mattmann; I Tobler
Journal: Arzneimittelforschung Date: 1983

7. The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients.

Authors: J M HINTON
Journal: Br J Pharmacol Chemother Date: 1961-02

7 in total

5 in total

Ambulatory motor activity monitoring to study the timecourse of hypnotic action.

1. Melancholia and barbiturates: a controlled EEG, body and eye movement study of sleep.

2. Hypnotic action and residual effects of a single bedtime dose of temazepam.

3. A single dose of benzodiazepine hypnotics alters the sleep EEG in the subsequent drug-free night.

4. Automated gas chromatography for studies of midazolam pharmacokinetics.

5. [Long term recording of motor activity: its use in research and clinical situations].

6. Midazolam and triazolam: hypnotic action and residual effects after a single bedtime dose.

7. The actions of amylobarbitone sodium, butobarbitone and quinalbarbitone sodium upon insomnia and nocturnal restlessness compared in psychiatric patients.

1. Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype.

2. Long-term 24-hour rest-activity pattern of sheep in stalls and in the field.

3. Long-term motor activity recording of dogs and the effect of sleep deprivation.

4. Effect of valerian on human sleep.

5. Environment shapes sleep patterns in a wild nocturnal primate.