Literature DB >> 6151583

Postmortem stability of benzodiazepines in blood and tissues.

B Levine, R V Blanke, J C Valentour.   

Abstract

The stability of benzodiazepines in blood and tissues was examined in this study. Specifically, diazepam, chlordiazepoxide, flurazepam, and their desalkyl metabolites were studied over several months. Diazepam, flurazepam, and N-1-desalkylflurazepam were stable when stored in blood at room temperature while chlordiazepoxide, norchlordiazepoxide, and nordiazepam were found to be unstable under similar storage conditions. Data from tissues containing these chemicals corroborated the results from blood.

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Year:  1983        PMID: 6151583

Source DB:  PubMed          Journal:  J Forensic Sci        ISSN: 0022-1198            Impact factor:   1.832


  2 in total

Review 1.  The influence of putrefaction and sample storage on post-mortem toxicology results.

Authors:  Danielle M Butzbach
Journal:  Forensic Sci Med Pathol       Date:  2009-11-28       Impact factor: 2.007

2.  Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry.

Authors:  Devin J Swiner; Sierra Jackson; George R Durisek; Bridget K Walsh; Yaman Kouatli; Abraham K Badu-Tawiah
Journal:  Anal Chim Acta       Date:  2019-07-09       Impact factor: 6.558

  2 in total

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