Literature DB >> 61502

The neurology of vitamin B12 deficiency. Metabolic mechanisms.

E H Reynolds.   

Abstract

The widely held view that the neurological and haematological complications of vitamin-B12 deficiency have different metabolic mechanisms appears unsound. It is suggested that the metabolic mechanisms involved are similar and that the neurological manifestations are the result of a secondary disturbance in folate metabolism as has already been postulated for the megaloblastosis.

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Year:  1976        PMID： 61502     DOI： 10.1016/s0140-6736(76)91213-7

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  7 in total

Review 1.  Multiple sclerosis and vitamin B12 metabolism.

Authors:  E H Reynolds
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-05       Impact factor: 10.154

2.  Vitamin b₁₂ deficiency and depression in the elderly: review and case report.

Authors:  Susan Hanna; Leonard Lachover; R P Rajarethinam
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2009

3.  Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.

Authors:  J J Dinn; D G Weir; S McCann; B Reed; P Wilson; J M Scott
Journal:  Ir J Med Sci       Date:  1980-01       Impact factor: 1.568

Review 4.  Biomarkers of cobalamin (vitamin B12) deficiency and its application.

Authors:  W Chatthanawaree
Journal:  J Nutr Health Aging       Date:  2011-03       Impact factor: 4.075

5.  Subacute combined degeneration of the cord due to folate deficiency: response to methyl folate treatment.

Authors:  E G Lever; R D Elwes; A Williams; E H Reynolds
Journal:  J Neurol Neurosurg Psychiatry       Date:  1986-10       Impact factor: 10.154

6.  Familial glucocorticoid deficiency with achalasia of the cardia associated with mixed neuropathy, long-tract degeneration and mild dementia.

Authors:  D B Grant; D B Dunger; I Smith; K Hyland
Journal:  Eur J Pediatr       Date:  1992-02       Impact factor: 3.183

7.  Subacute combined degeneration of the cord, dementia and parkinsonism due to an inborn error of folate metabolism.

Authors:  P T Clayton; I Smith; B Harding; K Hyland; J V Leonard; R J Leeming
Journal:  J Neurol Neurosurg Psychiatry       Date:  1986-08       Impact factor: 10.154
  7 in total

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