Literature DB >> 6150185

Inhibition of dithranol inflammation by free-radical scavengers.

M J Finnen, C M Lawrence, S Shuster.   

Abstract

Dithranol (anthralin) inflammation of forearm skin was completely inhibited by various scavengers of free radicals of the oxygen species. It is concluded that dithranol inflammation is initiated by formation of free radicals; these may act through lipid peroxidation and production of inflammatory endoperoxides or by a more direct mechanism.

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Year:  1984        PMID： 6150185     DOI： 10.1016/s0140-6736(84)91559-9

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  6 in total

1.  Effect of arachidonic acid on anthralin inflammation.

Authors:  C M Lawrence; S Shuster
Journal:  Br J Clin Pharmacol       Date:  1987-08       Impact factor: 4.335

2.  Characteristics and modulation of dithranol (anthralin)-induced skin irritation in the mouse ear model.

Authors:  M Viluksela
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

3.  Cocarcinogenic and tumor-promoting capabilities of anthralin.

Authors:  N Z Baturay; L D Trombetta
Journal:  Arch Dermatol Res       Date:  1988       Impact factor: 3.017

4.  Pharmacological studies on dithranol-induced irritative dermatitis in mice.

Authors:  L Kemény; M Csató; A Dobozy
Journal:  Arch Dermatol Res       Date:  1989       Impact factor: 3.017

5.  Effects of PAF-antagonists in mouse ear oedema induced by several inflammatory agents.

Authors:  M Merlos; L A Gómez; M Giral; M L Vericat; J García-Rafanell; J Forn
Journal:  Br J Pharmacol       Date:  1991-12       Impact factor: 8.739

Review 6.  The role of vitamin E in normal and damaged skin.

Authors:  F Nachbar; H C Korting
Journal:  J Mol Med (Berl)       Date:  1995-01       Impact factor: 4.599
  6 in total

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