Literature DB >> 6149858

GABA in brain tissue of paroxysmal (px) chick.

J D Firman, M M Beck.   

Abstract

An investigation was made of GABA in whole brain and brain regions of paroxysmal (px) chicks. Whole brain levels of GABA were higher (P less than 0.05) in px chicks than in normal siblings by day 10 post-hatching. GABA in brain areas containing degeneration of auditory and vestibular nuclei and tracts was also found to be higher (P less than 0.05) in px chicks. These data indicate that a dysfunction of the GABA pathway occurs early in the px syndrome, possibly as a causative factor.

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Year:  1984        PMID: 6149858     DOI: 10.1016/0742-8413(84)90176-2

Source DB:  PubMed          Journal:  Comp Biochem Physiol C Comp Pharmacol Toxicol        ISSN: 0742-8413


  1 in total

1.  Elevated brain GABA correlates with systemic dysfunctions in paroxysmal chick.

Authors:  P A Lewis; M M Beck; J H Douglas
Journal:  Metab Brain Dis       Date:  1994-12       Impact factor: 3.584

  1 in total

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