Literature DB >> 6149230

Cells resistant to cytotoxic drugs are recognized by monoclonal antibody.

C J O'Hara, J Grover, G B Price.   

Abstract

A monoclonal antibody produced by hybridomas obtained from a mouse immunized with drug-resistant cells recognizes certain hamster and human drug-resistant cell lines but not their drug-sensitive parental lines. Preliminary characterization of the antigen indicates that it is a molecule of approximately 180,000 daltons. This molecule may be the P-glycoprotein previously associated with a drug-resistance permeability barrier (Riordan JR, Ling V: J Biol Chem 254:12701-12705, 1979).

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6149230     DOI： 10.1007/bf00917144

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  25 in total

1.  A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gels.

Authors:  R C Switzer; C R Merril; S Shifrin
Journal:  Anal Biochem       Date:  1979-09-15       Impact factor: 3.365

2.  Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

Authors:  G Fairbanks; T L Steck; D F Wallach
Journal:  Biochemistry       Date:  1971-06-22       Impact factor: 3.162

3.  Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts.

Authors:  W T Beck; T J Mueller; L R Tanzer
Journal:  Cancer Res       Date:  1979-06       Impact factor: 12.701

4.  Resistance and cross-resistance of cultured leukemia P388 cells to vincristine, adriamycin, adriamycin analogs, and actinomycin D.

Authors:  L J Wilkoff; E A Dulmadge
Journal:  J Natl Cancer Inst       Date:  1978-12       Impact factor: 13.506

5.  Mechanism of cross-resistance between vincristine and daunorubicin in Ehrlich ascites tumor cells.

Authors:  T Skovsgaard
Journal:  Cancer Res       Date:  1978-12       Impact factor: 12.701

6.  In vivo characteristics of resistance and cross-resistance of an adriamycin-resistant subline of P388 leukemia.

Authors:  R K Johnson; M P Chitnis; W M Embrey; E B Gregory
Journal:  Cancer Treat Rep       Date:  1978-10

7.  Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability.

Authors:  J R Riordan; V Ling
Journal:  J Biol Chem       Date:  1979-12-25       Impact factor: 5.157

8.  DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression.

Authors:  P G Debenham; N Kartner; L Siminovitch; J R Riordan; V Ling
Journal:  Mol Cell Biol       Date:  1982-08       Impact factor: 4.272

9.  Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines.

Authors:  N Kartner; J R Riordan; V Ling
Journal:  Science       Date:  1983-09-23       Impact factor: 47.728

10.  A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

Authors:  J H Goldie; A J Coldman
Journal:  Cancer Treat Rep       Date:  1979 Nov-Dec
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.