Excretion of cadmium and change in the relative ratio of iso-cadmium-binding proteins during metamorphosis of fleshfly (Sarcophaga peregrina).

Cadmium (Cd) was accumulated in the larvae of Sarcophaga peregrina (fleshfly) by exposure through diet, and the metabolic fate of the accumulated Cd during metamorphosis was examined. Most of the Cd accumulated in the larvae was retained in the pupae, and 53% of that was excreted from the adults immediately after emergence. The Cd-binding protein induced in the larvae was degraded after pupation and the relative ratio of iso-Cd-binding proteins re-induced in the adults was different from that in the larvae. Copper content in the larvae was significantly reduced by Cd administration.