Literature DB >> 6148474

Recovery and inactivation of infectious retroviruses from factor VIII concentration.

J A Levy, G Mitra, M M Mozen.   

Abstract

The ability of infectious retroviruses to withstand the procedures used for factor VIII concentration was investigated. Mouse retroviruses added to human plasma survived these procedures and remained infectious in lyophilised samples of factor VIII. Lyophilised material had to be heated at 68 degrees C for several hours before substantial quantities of infectious virus became inactivated. These findings support the possible role of retroviruses in AIDS, and indicate that factor VIII concentrates must be heated to inactivate these infectious viruses.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6148474     DOI： 10.1016/s0140-6736(84)92627-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  10 in total

Review 1.  Enzyme-replacement therapy: problems and prospects.

Authors:  B Rademaker; J Raber
Journal:  Pharm Weekbl Sci       Date:  1989-10-20

2.  A University of California State-supported AIDS research award program--a unique state and university partnership in AIDS research.

Authors:  N K Das; C L Hopper; M Jencks; J Silva
Journal:  J Clin Immunol       Date:  1991-03       Impact factor: 8.317

Review 3.  Transmission of human immunodeficiency virus (HIV/HTLV-III/LAV): a review.

Authors:  M van der Graaf; R J Diepersloot
Journal:  Infection       Date:  1986 Sep-Oct       Impact factor: 3.553

4.  Bacterial expression of the acquired immunodeficiency syndrome retrovirus p24 gag protein and its use as a diagnostic reagent.

Authors:  D J Dowbenko; J R Bell; C V Benton; J E Groopman; H Nguyen; D Vetterlein; D J Capon; L A Lasky
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

5.  HTLV III antibodies and immunological alterations in hemophilia patients.

Authors:  E Seifried; G Pindur; H Stötter; F Porzsolt; H Rasche; V Erfle; R Hehlmann; H Heimpel
Journal:  Klin Wochenschr       Date:  1986-02-03

Review 6.  Pathogenesis of human immunodeficiency virus infection.

Authors:  J A Levy
Journal:  Microbiol Rev       Date:  1993-03

7.  Thermal inactivation of the acquired immunodeficiency syndrome virus, human T lymphotropic virus-III/lymphadenopathy-associated virus, with special reference to antihemophilic factor.

Authors:  J S McDougal; L S Martin; S P Cort; M Mozen; C M Heldebrant; B L Evatt
Journal:  J Clin Invest       Date:  1985-08       Impact factor: 14.808

Review 8.  Factor VIII, HIV and AIDS in haemophiliacs: an analysis of their relationship.

Authors:  E Papadopulos-Eleopulos; V F Turner; J M Papadimitriou; D Causer
Journal:  Genetica       Date:  1995       Impact factor: 1.082

9.  Guidelines for people responsible for education and day care of children with HTLV-III/LAV infection.

Authors:  G F Smith
Journal:  CMAJ       Date:  1986-07-15       Impact factor: 8.262

10.  Thermostability of human immunodeficiency virus (HIV-1) in a liquid matrix is far higher than that of an ecotropic murine leukemia virus.

Authors:  H Yoshikura
Journal:  Jpn J Cancer Res       Date:  1989-01
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.