| Literature DB >> 6148397 |
M Kingsford, N J Eggers, G Soteros, T J Maling, R J Shirkey.
Abstract
The dissolution behaviour of four commercial and two experimental formulations of frusemide tablets has been investigated using the USP rotating basket apparatus and pH 5.0 buffer at 37 degrees C as the test medium. There is a linear relationship between the percentage dissolution in 30 min and the bioavailability relative to an oral solution of frusemide over the bioavailability range 76-97%. Predicted bioavailabilities differed by no more than 2% from the measured values.Entities:
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Year: 1984 PMID： 6148397 DOI： 10.1111/j.2042-7158.1984.tb04446.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765