Literature DB >> 6147468

Spina bifida and in-utero exposure to valproate.

D Lindhout, H Meinardi.   

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Year:  1984        PMID： 6147468     DOI： 10.1016/s0140-6736(84)90557-9

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


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  11 in total

1.  The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, co-medication, and the presence of spina bifida.

Authors:  J G Omtzigt; H Nau; F J Los; L Pijpers; D Lindhout
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

2.  Theoretical characterization of SOME amides and esters DERIVATIVES of valproic acid.

Authors:  Nieves C Comelli; Patricio Fuentealba; Eduardo A Castro; Alicia H Jubert
Journal:  J Mol Model       Date:  2009-07-16       Impact factor: 1.810

3.  Prescribing in pregnancy. Epilepsy and anticonvulsant drugs.

Authors:  A Hopkins
Journal:  Br Med J (Clin Res Ed)       Date:  1987-02-21

4.  Pharmacokinetic aspects of drug effects in vitro: effects of serum protein binding on concentration and teratogenicity of valproic acid and 2-en-valproic acid in whole embryos in culture.

Authors:  C Lewandowski; S Klug; H Nau; D Neubert
Journal:  Arch Toxicol       Date:  1986-04       Impact factor: 5.153

5.  Valproic acid therapy and neural tube defects.

Authors:  A S Garden; R J Benzie; E M Hutton; D J Gare
Journal:  Can Med Assoc J       Date:  1985-04-15       Impact factor: 8.262

6.  Behavioral teratogenicity of valproic acid: selective effects on behavior after prenatal exposure to rats.

Authors:  C V Vorhees
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 7.  Treating recurrent affective disorders during and after pregnancy. What can be taken safely?

Authors:  M Schou
Journal:  Drug Saf       Date:  1998-02       Impact factor: 5.606

Review 8.  Management of epilepsy during pregnancy.

Authors:  Dina Battino; Torbjörn Tomson
Journal:  Drugs       Date:  2007       Impact factor: 9.546

9.  The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice.

Authors:  R S Hauck; H Nau
Journal:  Pharm Res       Date:  1992-07       Impact factor: 4.200

Review 10.  Differentiation between valproate-induced anticonvulsant effect, teratogenicity and hepatotoxicity. Aspects of species variation, pharmacokinetics, metabolism and implications of structural specificity for the development of alternative antiepileptic agents such as delta 2-valproate.

Authors:  H Nau; H Siemes
Journal:  Pharm Weekbl Sci       Date:  1992-06-19
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