Literature DB >> 6146918

Neuroleptic malignant syndrome.

W Knezevic, F L Mastaglia, R B Lefroy, A Fisher.   

Abstract

Three cases of the neuroleptic malignant syndrome, which complicated treatment with haloperidol, fluphenazine and, in one case, with several drugs, are described. All three patients recovered and, in two, levodopa appeared to modify the course of the condition. In one patient, myoclonus was present and has persisted. The pharmacological mechanisms involved in this syndrome are discussed.

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Year:  1984        PMID: 6146918     DOI: 10.5694/j.1326-5377.1984.tb103843.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  4 in total

Review 1.  Clinical features, pathogenesis and management of drug-induced rhabdomyolysis.

Authors:  C Köppel
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Mar-Apr

2.  Haloperidol-induced neuroleptic malignant syndrome in a 67-year-old woman with parkinsonism.

Authors:  T C Ryken; A N Merrell
Journal:  West J Med       Date:  1989-09

3.  Neuroleptic malignant syndrome: a case for electroconvulsive therapy.

Authors:  C C Harland; M M O'Leary; R Winters; J Owens; B Hayes; V Melikian
Journal:  Postgrad Med J       Date:  1990-01       Impact factor: 2.401

4.  Haloperidol-increased muscle tone in rats as a model of parkinsonian rigidity.

Authors:  E Lorenc-Koci; S Wolfarth; K Ossowska
Journal:  Exp Brain Res       Date:  1996-05       Impact factor: 1.972

  4 in total

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