| Literature DB >> 6146873 |
C Chilvers, M C Pike, D Forman, K Fogelman, M E Wadsworth.
Abstract
Examination of Hospital Inpatient Enquiry data for England and Wales for the years 1962-81 shows that the annual number of discharges with a diagnosis of undescended testicle has risen by a factor of 2.3. Cohort analysis suggests that the cumulative rate to age 15 of discharge for undescended testis has risen from 1.4% for the 1952 birth-cohort to 2.9% for the 1977 birth-cohort. Whether this is a reflection of an increase in true cryptorchidism is not known. Changes in known risk factors for cryptorchidism--exogenous oestrogen exposure, being first-born, and low birth-weight--cannot fully account for the apparent increase. With the tendency to carry out orchidopexies on apparently undescended testes at younger ages in order to preserve fertility, it is possible that a considerable number of boys with retractile testes that would have descended naturally at puberty are now being operated upon.Entities:
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Year: 1984 PMID: 6146873 DOI: 10.1016/s0140-6736(84)92697-7
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321