Literature DB >> 6146145

Naloxone reserves the inhibitory effects of dynorphin A on motor activity in the mouse.

M Ukai, S Yamada, T Kameyama.   

Abstract

Dynorphin-(1-17) (dynorphin A) significantly reduced the linear locomotion, rearing and grooming behaviors in mice using a newly devised multi-dimensional behavioral analyser. The behaviors inhibited by dynorphin A were dose-dependently antagonized by prior treatment with naloxone. The results suggest that dynorphin A-induced behavioral depression is mediated via opioid receptors in the mouse brain.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6146145     DOI： 10.1016/0091-3057(84)90206-5

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  4 in total

1.  An observational analysis of the effect of the selective kappa opioid agonist, U-50,488H, on feeding and related behaviours in the rat.

Authors:  A Jackson; S J Cooper
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

2.  Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.

Authors:  D P Devine; L Taylor; R K Reinscheid; F J Monsma; O Civelli; H Akil
Journal:  Neurochem Res       Date:  1996-11       Impact factor: 3.996

3.  Unlike beta-endorphin, dynorphin 1-13 does not cause retrograde amnesia for shuttle avoidance or inhibitory avoidance learning in rats.

Authors:  I Izquierdo; M A De Almeida; V R Emiliano
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

4.  Observational analysis of the effects of kappa opioid agonists an open field behaviour in the rat.

Authors:  A Jackson; S J Cooper
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.