Literature DB >> 6145491

Sensitivity of hippocampal neurons to glutamic acid and its analogues.

C Yamamoto, S Sawada.   

Abstract

In thin slices of the guinea-pig hippocampus, depolarizations induced by glutamate (Glu) and its analogues were studied by intracellular recording. It was found that Glu induced stereospecific responses, that L-Glu was more potent than homocysteate and N-methyl-D-aspartate. It is probable that the high-affinity uptake mechanism played a decisive role in termination of L-Glu excitation.

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Year:  1982        PMID: 6145491     DOI: 10.1016/0006-8993(82)91014-9

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  7 in total

1.  Some properties of ionic channels activated by excitatory amino acids in hippocampal neurons.

Authors:  C Yamamoto; H Sato
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

2.  Repetitive firing of CA1 hippocampal pyramidal cells elicited by dendritic glutamate: slow prepotentials and burst-pause pattern.

Authors:  J Storm; O Hvalby
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

3.  Blocking action of pentobarbital on receptors for excitatory amino acids in the guinea pig hippocampus.

Authors:  S Sawada; C Yamamoto
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

4.  Action of excitatory amino acids and their antagonists on hippocampal neurons.

Authors:  J J Hablitz
Journal:  Cell Mol Neurobiol       Date:  1985-12       Impact factor: 5.046

5.  Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.

Authors:  S Sawada; M Higashima; C Yamamoto
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

6.  Gamma-D-glutamylglycine and cis-2,3-piperidine dicarboxylate as antagonists of excitatory amino acids in the hippocampus.

Authors:  S Sawada; C Yamamoto
Journal:  Exp Brain Res       Date:  1984       Impact factor: 1.972

7.  Suppressing action of 2-amino-4-phosphonobutyric acid on mossy fiber-induced excitation in the guinea pig hippocampus.

Authors:  C Yamamoto; S Sawada; S Takada
Journal:  Exp Brain Res       Date:  1983       Impact factor: 1.972

  7 in total

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