Literature DB >> 6144751

Studies into the mode of action of non-steroidal anti-inflammatory drugs using a model of facsimile synovium.

A D Sedgwick, Y M Sin, A R Mackay, A Al-Duaij, D A Willoughby.   

Abstract

The effect of non-steroidal anti-inflammation produced in the 6-day old air pouch by carrageenan or calcium pyrophosphate crystals has been examined. The system is a very reproducible way of studying the cellular and vascular components of inflammation. Non-steroidal drugs have different profiles of activity when tested on the inflammation produced with the two irritants. In general, however, the tested compounds showed similar activity on individual models.

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Year:  1984        PMID： 6144751     DOI： 10.1111/j.2042-7158.1984.tb06933.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  8 in total

1.  Professor Derek Albert Willoughby (1930-2004).

Authors:  K D Rainsford
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473

2.  The subcutaneous air pouch model of synovium and the inflammatory response to heat aggregated gammaglobulin.

Authors:  I C Kowanko; T P Gordon; M A Rozenbilds; P M Brooks; P J Roberts-Thomson
Journal:  Agents Actions       Date:  1986-06

3.  Regional drug delivery I: permeability characteristics of the rat 6-day-old air pouch model of inflammation.

Authors:  S W Martin; A J Stevens; B S Brennan; M L Reis; L A Gifford; M Rowland; J B Houston
Journal:  Pharm Res       Date:  1995-12       Impact factor: 4.200

4.  Induction of a silica air-pouch granuloma in rat.

Authors:  W Paska; K J McDonald
Journal:  Agents Actions       Date:  1988-07

5.  The effects of celecoxib, a COX-2 selective inhibitor, on acute inflammation induced in irradiated rats.

Authors:  M T Khayyal; Mona A El-Ghazaly; R M El-Hazek; A S Nada
Journal:  Inflammopharmacology       Date:  2009-10-02       Impact factor: 4.473

6.  Anti-Inflammatory Properties and Chemical Characterization of the Essential Oils of Four Citrus Species.

Authors:  Jorge Luis Amorim; Daniel Luiz Reis Simas; Mariana Martins Gomes Pinheiro; Daniela Sales Alviano Moreno; Celuta Sales Alviano; Antonio Jorge Ribeiro da Silva; Patricia Dias Fernandes
Journal:  PLoS One       Date:  2016-04-18       Impact factor: 3.240

7.  Discovery of Novel Orally Active Tetrahydro-Naphthyl-N-Acylhydrazones with In Vivo Anti-TNF-α Effect and Remarkable Anti-Inflammatory Properties.

Authors:  Natália M Cordeiro; Rosana H C N Freitas; Carlos A M Fraga; Patricia D Fernandes
Journal:  PLoS One       Date:  2016-05-26       Impact factor: 3.240

8.  Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil.

Authors:  Graciela Rocha Donald; Patrícia Dias Fernandes; Fabio Boylan
Journal:  Evid Based Complement Alternat Med       Date:  2016-07-31       Impact factor: 2.629
  8 in total

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