Literature DB >> 6144367

Dopamine D2 receptors in substantia nigra in schizophrenia.

R Owen, F Owen, M Poulter, T J Crow.   

Abstract

Dopamine D2 receptors were assessed in samples of substantia nigra from controls and schizophrenics. Specific [3H]spiperone binding was significantly increased in both neuroleptic-free and neuroleptic-treated schizophrenics. This supports our previous suggestion that the increase in D2 receptors observed in striatum of schizophrenics is not wholly due to neuroleptic medication.

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Year:  1984        PMID： 6144367     DOI： 10.1016/0006-8993(84)90798-4

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

1.  The dopamine dilemma: using stimulants and antipsychotics concurrently.

Authors:  Jason Yanofski
Journal:  Psychiatry (Edgmont)       Date:  2010-06

2.  Nigral Stress-Induced Dopamine Release in Clinical High Risk and Antipsychotic-Naïve Schizophrenia.

Authors:  Huai-Hsuan Tseng; Jeremy J Watts; Michael Kiang; Ivonne Suridjan; Alan A Wilson; Sylvain Houle; Pablo M Rusjan; Romina Mizrahi
Journal:  Schizophr Bull       Date:  2018-04-06       Impact factor: 9.306

3.  3H-spiperone binding sites in post-mortem brains from schizophrenic patients: relationship to neuroleptic drug treatment, abnormal movements, and positive symptoms.

Authors:  J Kornhuber; P Riederer; G P Reynolds; H Beckmann; K Jellinger; E Gabriel
Journal:  J Neural Transm       Date:  1989       Impact factor: 3.575

Review 4.  Basal ganglia pathology in schizophrenia: dopamine connections and anomalies.

Authors:  Emma Perez-Costas; Miguel Melendez-Ferro; Rosalinda C Roberts
Journal:  J Neurochem       Date:  2010-01-20       Impact factor: 5.372

5.  Dopamine D2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects.

Authors:  Robert M Kessler; Neil D Woodward; Patrizia Riccardi; Rui Li; M Sib Ansari; Sharlett Anderson; Benoit Dawant; David Zald; Herbert Y Meltzer
Journal:  Biol Psychiatry       Date:  2009-02-28       Impact factor: 13.382

6.  Comparison between the efficacies of Risperidone with Haloperidol in the treatment of attention-deficit hyperactivity disorder (ADHD) among preschoolers: a randomized double-blind clinical trial.

Authors:  Forough Riahi; Ashraf Tashakori; Leila Abdi
Journal:  Electron Physician       Date:  2016-09-20

7.  Putative presynaptic dopamine dysregulation in schizophrenia is supported by molecular evidence from post-mortem human midbrain.

Authors:  T D Purves-Tyson; S J Owens; D A Rothmond; G M Halliday; K L Double; J Stevens; T McCrossin; C Shannon Weickert
Journal:  Transl Psychiatry       Date:  2017-01-17       Impact factor: 6.222

8.  Neuropathological changes in the substantia nigra in schizophrenia but not depression.

Authors:  M R Williams; K Galvin; B O'Sullivan; C D MacDonald; E W K Ching; F Turkheimer; O D Howes; R K B Pearce; S R Hirsch; M Maier
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2013-12-29       Impact factor: 5.270
  8 in total

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