Literature DB >> 6143285

Biochemistry of the hypothalamus in Parkinson's disease.

F Javoy-Agid, M Ruberg, L Pique, X Bertagna, H Taquet, J M Studler, F Cesselin, J Epelbaum, Y Agid.   

Abstract

We assayed the content of neurotransmitters (or their synthesizing enzymes) and neuropeptides in the hypothalamus of control and parkinsonian brains post mortem. Only dopamine concentrations were lower than normal in Parkinson's disease, suggesting that deficiency in hypothalamic dopamine transmission may play a role in the autonomic and endocrine abnormalities of this disorder.

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Year:  1984        PMID： 6143285     DOI： 10.1212/wnl.34.5.672

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  11 in total

1.  Determination of beta-endorphin and substance P in small volumes of human cerebrospinal fluid.

Authors:  K Henning; T M Wallasch; H Przuntek
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

2.  Cold caloric microcirculatory reflex disturbance in patients with Parkinson's disease.

Authors:  O I Kolev; S Pedersson; G Nilsson; L Tibbling
Journal:  Clin Auton Res       Date:  1997-04       Impact factor: 4.435

Review 3.  The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson's disease.

Authors:  Yan Shen; Xingfang Guo; Chao Han; Fang Wan; Kai Ma; Shiyi Guo; Luxi Wang; Yun Xia; Ling Liu; Zhicheng Lin; Jinsha Huang; Nian Xiong; Tao Wang
Journal:  Cell Mol Life Sci       Date:  2017-06-16       Impact factor: 9.261

4.  Proteomics and bioinformatics analysis of mouse hypothalamic neurogenesis with or without EPHX2 gene deletion.

Authors:  Lijun Zhong; Juntuo Zhou; Dawei Wang; Xiajuan Zou; Yaxin Lou; Dan Liu; Bin Yang; Yi Zhu; Xiaoxia Li
Journal:  Int J Clin Exp Pathol       Date:  2015-10-01

Review 5.  The hypothalamus in MPTP-induced parkinsonism.

Authors:  R Sandyk; R P Iacono; S R Kay
Journal:  Ital J Neurol Sci       Date:  1990-08

Review 6.  A New Perspective for Parkinson's Disease: Circadian Rhythm.

Authors:  Siyue Li; Yali Wang; Fen Wang; Li-Fang Hu; Chun-Feng Liu
Journal:  Neurosci Bull       Date:  2016-12-19       Impact factor: 5.203

Review 7.  The hypothalamus in Parkinson disease.

Authors:  R Sandyk; R P Iacono; C R Bamford
Journal:  Ital J Neurol Sci       Date:  1987-06

8.  Hyperthermic syndromes and impairment of the dopaminergic system: a clinical study.

Authors:  L Figà-Talamanca; C Gualandi
Journal:  Ital J Neurol Sci       Date:  1989-02

9.  Plasma profiles of adrenocorticotropic hormone, cortisol, growth hormone and prolactin in patients with untreated Parkinson's disease.

Authors:  G Bellomo; L Santambrogio; M Fiacconi; A M Scarponi; G Ciuffetti
Journal:  J Neurol       Date:  1991-02       Impact factor: 4.849

10.  Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue.

Authors:  Rana Soylu-Kucharz; Natalie Adlesic; Barbara Baldo; Deniz Kirik; Åsa Petersén
Journal:  Sci Rep       Date:  2015-09-30       Impact factor: 4.379
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