Hierarchial thermodynamic approach to the brain.

A thermodynamic approach to understanding the brain is presented. Thermodynamics may be extended to "higher than molecule" levels. The role of the concept of entropy in thermodynamic-based nonthermodynamic systems has been discussed. Static and dynamic structures, cooperative and competitive mechanisms and some of their neurobiological applications are discussed. Postsynaptic membrane noises, dynamic synaptic activity, synaptogenesis, plasticity, retinotopy and perception have been considered as self-organizing neural structures appearing at different hierarchical levels.