Literature DB >> 614147

[Differences of capacity of human erythrocytes of newborn infants and adults and trypsin-treated erythrocytes to bind rubella virus hemagglutinin].

A Negro Ponzi, A Pugliese.   

Abstract

Rubella virus hemagglutinating (HA) antigen shows different titers against non treated, trypsin-modified and cord blood human erythrocytes. Trypsin-modified erythrocytes give titers eleven fold higher, and cord blood red cells sixteen fold higher than those seen with the non treated cells. These differences in sensitivity agree with a different ability to bind HA antigen: with an excess of antigen cord blood erythrocytes bind two, and trypsin-modified erythrocytes three times as much antigen was bound by non treated cells. The amount of bound antigen shows little or no dependence on 4 degrees or 37 degrees C temperatures.

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Year:  1977        PMID: 614147

Source DB:  PubMed          Journal:  G Batteriol Virol Immunol        ISSN: 0390-5462


  1 in total

1.  Rubella virus hemagglutination with human and animal erythrocytes: effect of age and trypsinization.

Authors:  A N Ponzi; A Pugliese; P Pertusio
Journal:  J Clin Microbiol       Date:  1978-05       Impact factor: 5.948

  1 in total

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