Literature DB >> 6141228

Release of aspartate and glutamate caused by chloride reduction in synaptosomal incubation media.

J A Hardy, R J Boakes, D J Thomas, A M Kidd, J A Edwardson, M Virmani, J Turner, P R Dodd.   

Abstract

Release of the amino acid neurotransmitter candidates aspartate and glutamate from synaptosomes can be stimulated by reduction of [Cl-] in the incubation medium by replacement with the impermeant anions propionate and isethionate. Replacement by the permeant anion Br- is without effect on amino acid release. This release offers a biochemical method of studying the Cl-ion channel in CNS membrane.

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Year:  1984        PMID: 6141228     DOI: 10.1111/j.1471-4159.1984.tb02763.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN: 0022-3042            Impact factor:   5.372


  2 in total

1.  GABAergic modulation of catecholamine release from cultured bovine adrenal chromaffin cells. Evidence for the involvement of Cl(-)-dependent Ca2+ entry.

Authors:  S Kitayama; K Morita; T Dohi; A Tsujimoto
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-05       Impact factor: 3.000

2.  Chloride dependence of the K(+)-stimulated release of taurine from synaptosomes.

Authors:  R Sánchez Olea; H Pasantes-Morales
Journal:  Neurochem Res       Date:  1990-05       Impact factor: 3.996

  2 in total

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