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Literature DB >> 6141067

Synthesis of the nuclear protein cyclin in growing, senescent and morphologically transformed human skin fibroblasts.

Abstract

Quantitative two-dimensional gel electrophoretic analysis (IEF) of the nuclear polypeptide cyclin in normal human skin biopsies, growing and senescent fibroblasts and morphologically transformed skin fibroblasts (limited life span) has revealed a direct correlation between the levels of this protein and proliferative state of the cells. These results strengthen the notion that cyclin may be a key component of the pathway(s) that control cell proliferation.

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Year: 1984 PMID： 6141067 DOI： 10.1016/0014-5793(84)80006-x

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

11 in total

1. Cell proliferation in human coronary arteries.

Authors: D Gordon; M A Reidy; E P Benditt; S M Schwartz
Journal: Proc Natl Acad Sci U S A Date: 1990-06 Impact factor: 11.205

2. Proliferation-sensitive nuclear phosphoprotein "dividin" is synthesized almost exclusively during S phase of the cell cycle in human AMA cells.

Authors: J E Celis; S Nielsen
Journal: Proc Natl Acad Sci U S A Date: 1986-11 Impact factor: 11.205

3. Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase.

Authors: J E Celis; A Celis
Journal: Proc Natl Acad Sci U S A Date: 1985-05 Impact factor: 11.205

4. Expression of the transformation-sensitive protein "cyclin" in normal human epidermal basal cells and simian virus 40-transformed keratinocytes.

Authors: J E Celis; S J Fey; P M Larsen; A Celis
Journal: Proc Natl Acad Sci U S A Date: 1984-05 Impact factor: 11.205

5. Nuclear antigens in the HeLa cell cycle.

Authors: Z M Banjar; R C Briggs; L S Hnilica; J L Stein; G S Stein
Journal: Mol Cell Biochem Date: 1985-07 Impact factor: 3.396

6. Resveratrol inhibits development of experimental endometriosis in vivo and reduces endometrial stromal cell invasiveness in vitro.

Authors: Kaylon L Bruner-Tran; Kevin G Osteen; Hugh S Taylor; Anna Sokalska; Kaitlin Haines; Antoni J Duleba
Journal: Biol Reprod Date: 2010-09-15 Impact factor: 4.285

Synthesis of the nuclear protein cyclin in growing, senescent and morphologically transformed human skin fibroblasts.

1. Cell proliferation in human coronary arteries.

2. Proliferation-sensitive nuclear phosphoprotein "dividin" is synthesized almost exclusively during S phase of the cell cycle in human AMA cells.

3. Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase.

4. Expression of the transformation-sensitive protein "cyclin" in normal human epidermal basal cells and simian virus 40-transformed keratinocytes.

5. Nuclear antigens in the HeLa cell cycle.

6. Resveratrol inhibits development of experimental endometriosis in vivo and reduces endometrial stromal cell invasiveness in vitro.

7. Epidermal growth factor inhibits the synthesis of the nuclear protein cyclin in A431 human carcinoma cells.

8. Expression of proliferating cell nuclear antigen during the cell cycle of human diploid fibroblasts.

9. Proliferating cell nuclear antigen (PCNA): a new marker to study human colonic cell proliferation.

10. Individual nuclei in polykaryons can control cyclin distribution and DNA synthesis.