Literature DB >> 6140681

Voltage-operated channels induced by foreign messenger RNA in Xenopus oocytes.

C B Gundersen, R Miledi, I Parker.   

Abstract

Poly(A)+ messenger RNA (mRNA) extracted from rat brains or from cat muscles was injected into Xenopus laevis oocytes. This led to the incorporation of voltage-operated Na+ and K+ channels into the oocyte membrane. These channels are not normally present in the oocyte and presumably result from the synthesis and processing of proteins coded by the injected mRNA. Tetrodotoxin blocked the Na+ channels induced by mRNA derived from either innervated or denervated muscle.

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Year:  1983        PMID： 6140681     DOI： 10.1098/rspb.1983.0092

Source DB:  PubMed          Journal:  Proc R Soc Lond B Biol Sci        ISSN： 0950-1193


  23 in total

Review 1.  Use of Xenopus oocytes for the functional expression of plasma membrane proteins.

Authors:  E Sigel
Journal:  J Membr Biol       Date:  1990-09       Impact factor: 1.843

2.  Endogenous D-glucose transport in oocytes of Xenopus laevis.

Authors:  W M Weber; W Schwarz; H Passow
Journal:  J Membr Biol       Date:  1989-10       Impact factor: 1.843

3.  Expressional potency of mRNAs encoding receptors and voltage-activated channels in the postmortem rat brain.

Authors:  D S Ragsdale; R Miledi
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-01       Impact factor: 11.205

4.  Gating currents of inactivating and non-inactivating potassium channels expressed in Xenopus oocytes.

Authors:  W Stühmer; F Conti; M Stocker; O Pongs; S H Heinemann
Journal:  Pflugers Arch       Date:  1991-05       Impact factor: 3.657

5.  Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels.

Authors:  C Methfessel; V Witzemann; T Takahashi; M Mishina; S Numa; B Sakmann
Journal:  Pflugers Arch       Date:  1986-12       Impact factor: 3.657

6.  Expression of Ba currents in Xenopus oocyte injected with pregnant rat myometrium mRNA.

Authors:  F Fournier; E Honoré; G Brûlé; J Mironneau; P Guilbault
Journal:  Pflugers Arch       Date:  1989-04       Impact factor: 3.657

7.  Change in desensitization of cat muscle acetylcholine receptor caused by coexpression of Torpedo acetylcholine receptor subunits in Xenopus oocytes.

Authors:  K Sumikawa; R Miledi
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

8.  Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid.

Authors:  E Sigel
Journal:  J Physiol       Date:  1987-05       Impact factor: 5.182

9.  Effects of veratridine on single neuronal sodium channels expressed in Xenopus oocytes.

Authors:  E Sigel
Journal:  Pflugers Arch       Date:  1987-09       Impact factor: 3.657

10.  Receptors for neuropeptides are induced by exogenous poly(A)+ RNA in oocytes from Xenopus laevis.

Authors:  W Meyerhof; S Morley; J Schwarz; D Richter
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205
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