| Literature DB >> 6140546 |
K D Miller, R D Gibbs, M M Mulligan, T B Nutman, D P Francis.
Abstract
Fourteen adult volunteers were given a series of three 0.1 ml (2.0 micrograms of antigen protein) intradermal doses of hepatitis B virus vaccine (Merck). An antibody (anti-HBs) response was induced in 10 of 12 (83%) who were antibody negative at the start of the study. Two participants who had anti-HBs before vaccination had a significant increase in serum antibody. The two participants with no antibody response were the oldest members of the study group. Side-effects of the vaccine were limited to local reactions at the site of administration.Entities:
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Year: 1983 PMID： 6140546 DOI： 10.1016/s0140-6736(83)90800-0
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321