Literature DB >> 6140544

15O positron emission tomographic scanning in predominantly never-treated acute schizophrenic patients.

G Sheppard, J Gruzelier, R Manchanda, S R Hirsch, R Wise, R Frackowiak, T Jones.   

Abstract

Positron emission tomography with oxygen-15 was used to compare regional cerebral blood flow and the regional cerebral metabolic rate of oxygen in a group of predominantly never-treated, acute schizophrenic patients and in matched controls. The results of this study did not support the hypothesis that schizophrenics have reduced frontal blood flow and/or metabolism; and only equivocal support was obtained for the hypothesis that metabolism within the basal ganglia is reduced in schizophrenics. However, support was obtained for the hypothesis that an abnormality in hemisphere laterality may underlie schizophrenic illness.

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Year:  1983        PMID： 6140544     DOI： 10.1016/s0140-6736(83)90798-5

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  19 in total

Review 1.  Functional brain mapping of psychopathology.

Authors:  G D Honey; P C Fletcher; E T Bullmore
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2.  Resting quantitative cerebral blood flow in schizophrenia measured by pulsed arterial spin labeling perfusion MRI.

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Review 3.  The relevance to psychiatry of recent advances in functional imaging.

Authors:  E M Joyce
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-06       Impact factor: 10.154

Review 4.  Structural and functional brain imaging in schizophrenia.

Authors:  J M Cleghorn; R B Zipursky; S J List
Journal:  J Psychiatry Neurosci       Date:  1991-07       Impact factor: 6.186

5.  Lateralisation of cortical function during cognitive tasks: regional cerebral blood flow studies of normal individuals and patients with schizophrenia.

Authors:  K F Berman; D R Weinberger
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-02       Impact factor: 10.154

6.  Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism, and functional brain connectivity.

Authors:  Neil Dawson; Rhiannon J Thompson; Allan McVie; David M Thomson; Brian J Morris; Judith A Pratt
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7.  Hypermetabolic pattern in frontal cortex and other brain regions in unmedicated schizophrenia patients. Results from a FDG-PET study.

Authors:  M Soyka; W Koch; H J Möller; T Rüther; K Tatsch
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2005-04-18       Impact factor: 5.270

8.  Striatal activity in borderline personality disorder with comorbid intermittent explosive disorder: sex differences.

Authors:  M Mercedes Perez-Rodriguez; Erin A Hazlett; Erin L Rich; Luis H Ripoll; Daniel M Weiner; Nicole Spence; Marianne Goodman; Harold W Koenigsberg; Larry J Siever; Antonia S New
Journal:  J Psychiatr Res       Date:  2012-03-29       Impact factor: 4.791

9.  Left globus pallidus abnormality in never-medicated patients with schizophrenia.

Authors:  T S Early; E M Reiman; M E Raichle; E L Spitznagel
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

10.  Effects of sulpiride and chlorpromazine on regional cerebral glucose metabolism in schizophrenic patients as determined by positron emission tomography.

Authors:  G Wik; F A Wiesel; I Sjögren; G Blomqvist; T Greitz; S Stone-Elander
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530
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