Literature DB >> 6139740

An investigation of the factors involved in increased adherence of C. albicans to epithelial cells mediated by E. coli.

H C Makrides, T W MacFarlane.   

Abstract

An in vitro study was carried out in order to investigate the effect of Escherichia coli on the adherence of Candida albicans to epithelial cells. Pre-incubation of HeLa cell monolayers with E. coli cell suspensions resulted in a large, significant increase in candidal adherence. Similar increases in adherence to HeLa cells were observed when incubation of C. albicans and HeLa cell monolayers was carried out in the presence of a mannose-specific lectin, concanavalin A. The enhanced adhesion of C. albicans due to both E. coli and concanavalin A was significantly reduced in the presence of mannose and alpha-methyl-D-mannoside although both sugars alone significantly increased candidal adherence. These studies indicate that the increased candidal adherence due to the presence of E. coli is mediated by the presence of fimbriae on the bacterial cells and mannose-like receptors on both the surfaces of C. albicans and the epithelial cells.

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Year:  1983        PMID: 6139740

Source DB:  PubMed          Journal:  Microbios        ISSN: 0026-2633


  5 in total

1.  An intestinal Candida albicans model for monomicrobial and polymicrobial biofilms and effects of hydrolases and the Bgl2 ligand.

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2.  Influence of growth conditions on cell surface hydrophobicity of Candida albicans and Candida glabrata.

Authors:  K C Hazen; B J Plotkin; D M Klimas
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

3.  Role of menthol in treatment of candidial napkin dermatitis.

Authors:  Ali Mohammad Sabzghabaee; Firouzeh Nili; Alireza Ghannadi; Nastaran Eizadi-Mood; Maryam Anvari
Journal:  World J Pediatr       Date:  2011-01-05       Impact factor: 9.186

4.  Unraveling the Antibiofilm Activity of a New Nanogold Resin for Dentures and Epithesis.

Authors:  Vera Ivanovic; Danica Popovic; Sanja Petrovic; Rebeka Rudolf; Peter Majerič; Milos Lazarevic; Igor Djordjevic; Vojkan Lazic; Milena Radunovic
Journal:  Pharmaceutics       Date:  2022-07-21       Impact factor: 6.525

Review 5.  Superficial Mycoses Associated with Diaper Dermatitis.

Authors:  Alexandro Bonifaz; Rubí Rojas; Andrés Tirado-Sánchez; Dinora Chávez-López; Carlos Mena; Luz Calderón; Ponce-Olivera Rosa María
Journal:  Mycopathologia       Date:  2016-05-19       Impact factor: 2.574

  5 in total

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