| Literature DB >> 6139571 |
B Pichini, J R Ecker, C Grose, R W Hyman.
Abstract
Varicella-zoster virus (VZV) was isolated from two separate sites in each of three patients with shingles (herpes zoster). The DNAs of the six VZV isolates were compared by high-resolution restriction endonuclease analysis with HindIII, KpnI, and HpaI. DNA cleavage patterns for each pair of VZV isolates were indistinguishable. These studies suggest that clinical shingles is the manifestation of a single VZV strain that becomes reactivated and causes both a viraemia and a dermatomal exanthem.Entities:
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Year: 1983 PMID： 6139571 DOI： 10.1016/s0140-6736(83)91271-0
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321