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Literature DB >> 6139294

Negative inotropic effect of some H2-receptor antagonists on the isolated human atria.

G Coruzzi, E Poli, F Fesani, D Medici, G Bertaccini.

Abstract

H2-Receptor antagonists were found to possess in various degrees a negative inotropic effect on human atria in vitro. This effect seemed to be independent of H2-receptor blockade and, at least in the case of oxmetidine, seemed to involve calcium ion transport and/or utilization.

Entities: Chemical Species

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Year: 1983 PMID： 6139294 DOI： 10.1007/bf01990372

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

7 in total

1. Cardiac effects of the new H2-receptor antagonists.

Authors: G Coruzzi; E Poli; G Bertaccini
Journal: Agents Actions Date: 1983-04

2. Effect of some new H2-receptor antagonists on gastrointestinal motility.

Authors: G Bertaccini; E Poli; M Adami; G Coruzzi
Journal: Agents Actions Date: 1983-04

3. Ranitidine-induced bradycardia.

Authors: E Camarri; E Chirone; G Fanteria; M Zocchi
Journal: Lancet Date: 1982-07-17 Impact factor: 79.321

Review 4. Evidence for and against heterogeneity in the histamine H2-receptor population.

Authors: G Bertaccini; G Coruzzi
Journal: Pharmacology Date: 1981 Impact factor: 2.547

5. Effects of histamine on human isolated heart muscle: comparison with effects of noradrenaline.

Authors: R W Gristwood; J C Lincoln; D A Owen
Journal: J Pharm Pharmacol Date: 1980-02 Impact factor: 3.765

6. Effect of some new Histamine H2-receptor antagonists on the guinea-pig papillary muscle.

Authors: G Bertaccini; G Coruzzi
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1981-11 Impact factor: 3.000

7. Electrophysiologic properties of cimetidine in man.

Authors: L Gould; C V Reddy; B K Singh; B Zen
Journal: Pacing Clin Electrophysiol Date: 1981-01 Impact factor: 1.976

7 in total

1. Cardiovascular effects of ranitidine and cimetidine during acute myocardial ischaemia in anaesthetized dogs.

Authors: S Dai
Journal: Agents Actions Date: 1986-10

Review 2. Safety of acid-suppressing drugs.

Authors: R A Smallwood; R G Berlin; N Castagnoli; H P Festen; C J Hawkey; S K Lam; M J Langman; P Lundborg; A Parkinson
Journal: Dig Dis Sci Date: 1995-02 Impact factor: 3.199

Negative inotropic effect of some H2-receptor antagonists on the isolated human atria.

1. Cardiac effects of the new H2-receptor antagonists.

2. Effect of some new H2-receptor antagonists on gastrointestinal motility.

3. Ranitidine-induced bradycardia.

Review 4. Evidence for and against heterogeneity in the histamine H2-receptor population.

5. Effects of histamine on human isolated heart muscle: comparison with effects of noradrenaline.

6. Effect of some new Histamine H2-receptor antagonists on the guinea-pig papillary muscle.

7. Electrophysiologic properties of cimetidine in man.

1. Cardiovascular effects of ranitidine and cimetidine during acute myocardial ischaemia in anaesthetized dogs.

Review 2. Safety of acid-suppressing drugs.

3. Negative chronotropic effects of nizatidine.

4. Action of the new H2-antagonist, DA 4577, on different in vitro and in vivo preparations.

5. Changes in the effects of nizatidine and famotidine on cardiac performance after pretreatment with ranitidine.

6. Relaxant effect of the H2-receptor antagonist oxmetidine on guinea-pig and human airways.

7. Effects of ranitidine and cimetidine on experimentally induced ventricular arrhythmias in anaesthetized rats.