Literature DB >> 6138989

Metabolism of the broad-spectrum antiviral agent, 9-(S)-(2,3-dihydroxypropyl) adenine, in different cell lines.

I Votruba, A Holý, E De Clercq.   

Abstract

9-(S)-(2,3-dihydroxypropyl)adenine [(S)-DHPA] did not undergo metabolic changes in any of the eleven cell lines tested. In these, it exhibited a varying antiviral activity against vesicular stomatitis virus (VSV), which appeared to correlate with the relative amounts of (S)-DHPA that had become cell-associated during virus infection.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6138989

Source DB:  PubMed          Journal:  Acta Virol        ISSN： 0001-723X            Impact factor:   1.162


  5 in total

1.  Inhibition of SAH-hydrolase activity during seed germination leads to deregulation of flowering genes and altered flower morphology in tobacco.

Authors:  Jaroslav Fulneček; Roman Matyášek; Ivan Votruba; Antonín Holý; Kateřina Křížová; Aleš Kovařík
Journal:  Mol Genet Genomics       Date:  2011-01-28       Impact factor: 3.291

Review 2.  A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets for the prevention of HIV infection.

Authors:  Tanuja N Gengiah; Cheryl Baxter; Leila E Mansoor; Ayesha Bm Kharsany; Salim S Abdool Karim
Journal:  Expert Opin Investig Drugs       Date:  2012-03-07       Impact factor: 6.206

3.  Efficacy of S-adenosylhomocysteine hydrolase inhibitors, D-eritadenine and (S)-DHPA, against the growth of Cryptosporidium parvum in vitro.

Authors:  Vlasta Ctrnáctá; Jason M Fritzler; Mária Surinová; Ivan Hrdý; Guan Zhu; Frantisek Stejskal
Journal:  Exp Parasitol       Date:  2010-04-20       Impact factor: 2.011

4.  Structural basis of RNA cap modification by SARS-CoV-2.

Authors:  Thiruselvam Viswanathan; Shailee Arya; Siu-Hong Chan; Shan Qi; Nan Dai; Anurag Misra; Jun-Gyu Park; Fatai Oladunni; Dmytro Kovalskyy; Robert A Hromas; Luis Martinez-Sobrido; Yogesh K Gupta
Journal:  Nat Commun       Date:  2020-07-24       Impact factor: 14.919

5.  Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus.

Authors:  Thiruselvam Viswanathan; Shailee Arya; Siu-Hong Chan; Shan Qi; Nan Dai; Robert A Hromas; Jun-Gyu Park; Fatai Oladunni; Luis Martinez-Sobrido; Yogesh K Gupta
Journal:  bioRxiv       Date:  2020-04-26
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.