| Literature DB >> 6138820 |
J Takemura, Y Seino, S Nishi, H Ishida, M Sakita, T Taminato, T Chiba, H Imura.
Abstract
The effects of PGE2 and PGD2 on gastric somatostatin and gastrin releases were investigated using the isolated perfused rat stomach. In the presence of 5.5 mM glucose, the infusion of PGE2 elicited a significant augmentation in somatostatin release, but suppressed gastrin secretion from the perfusate. On the other hand, PGD2 did not affect somatostatin release, although the gastrin secretion decreased significantly, the same as after PGE2 infusion. These results suggest that PGE2 and PGD2 may be important in the regulation of gastric endocrine function, but that PGD2 does not affect gastric somatostatin secretion.Entities:
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Year: 1983 PMID： 6138820 DOI： 10.1016/0167-0115(83)90267-7
Source DB: PubMed Journal: Regul Pept ISSN： 0167-0115