Literature DB >> 6138360

Reappearance of beta-adrenergic receptors after isoproterenol treatment in intact C6-cells.

C Hertel, M Staehelin.   

Abstract

The reappearance of beta-adrenergic receptors in C6-glioma cells after desensitization with isoproterenol was studied using the antagonist [3H]CGP-12177. Reappearance had the following properties: (a) it occurred in intact cells only, (b) it was temperature dependent, (c) it required an Na+/H+ gradient, low intracellular Ca2+ activity, and (d) it required ATP, and (e) intact lysosomes. The results suggest endocytosis and recycling of the beta-adrenergic receptor after agonist treatment.

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Year:  1983        PMID： 6138360      PMCID： PMC2112695          DOI： 10.1083/jcb.97.5.1538

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  29 in total

1.  Evidence for internalization of the recognition site of beta-adrenergic receptors during receptor subsensitivity induced by (-)-isoproterenol.

Authors:  D M Chuang; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

2.  Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

Authors:  S Ohkuma; B Poole
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

Review 3.  Commentary. Lysosomotropic agents.

Authors:  C de Duve; T de Barsy; B Poole; A Trouet; P Tulkens; F Van Hoof
Journal:  Biochem Pharmacol       Date:  1974-09-15       Impact factor: 5.858

4.  Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly.

Authors:  M W Kirschner; R C Williams; M Weingarten; J C Gerhart
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

5.  Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: apparent inhibition of receptor recycling.

Authors:  C Tietze; P Schlesinger; P Stahl
Journal:  Biochem Biophys Res Commun       Date:  1980-03-13       Impact factor: 3.575

6.  Refinement of the coomassie blue method of protein quantitation. A simple and linear spectrophotometric assay for less than or equal to 0.5 to 50 microgram of protein.

Authors:  T Spector
Journal:  Anal Biochem       Date:  1978-05       Impact factor: 3.365

7.  A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

Authors:  A De Lean; J M Stadel; R J Lefkowitz
Journal:  J Biol Chem       Date:  1980-08-10       Impact factor: 5.157

8.  Differentiated rat glial cell strain in tissue culture.

Authors:  P Benda; J Lightbody; G Sato; L Levine; W Sweet
Journal:  Science       Date:  1968-07-26       Impact factor: 47.728

9.  Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex.

Authors:  A M Tartakoff; P Vassalli
Journal:  J Exp Med       Date:  1977-11-01       Impact factor: 14.307

10.  Comparative studies of intracellular transport of secretory proteins.

Authors:  A Tartakoff; P Vassalli; M Détraz
Journal:  J Cell Biol       Date:  1978-12       Impact factor: 10.539
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  9 in total

1.  Localization of beta-adrenergic receptors in A431 cells in situ. Effect of chronic exposure to agonist.

Authors:  H Y Wang; M Berrios; C C Malbon
Journal:  Biochem J       Date:  1989-10-15       Impact factor: 3.857

2.  Evidence for the rapid internalization and recycling of lutropin receptors in rat testis Leydig cells.

Authors:  A D Habberfield; C J Dix; B A Cooke
Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

3.  Beta-adrenergic [( 3H]CGP-12177) binding to brain slices and single intact pineal glands.

Authors:  M Wilkinson; D A Wilkinson
Journal:  Neurochem Res       Date:  1985-06       Impact factor: 3.996

4.  Enhancement of the recycling and activation of beta-adrenergic receptor by Rab4 GTPase in cardiac myocytes.

Authors:  Catalin M Filipeanu; Fuguo Zhou; May L Lam; Kenneth E Kerut; William C Claycomb; Guangyu Wu
Journal:  J Biol Chem       Date:  2006-02-16       Impact factor: 5.157

5.  Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells.

Authors:  M E Ullian; S L Linas
Journal:  J Clin Invest       Date:  1989-09       Impact factor: 14.808

6.  Regulation of beta-adrenoceptors in the guinea-pig sinoatrial node.

Authors:  F D Russell; A R Kompa; P Molenaar; R J Summers
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-05       Impact factor: 3.000

7.  Human platelet beta 2-adrenoceptors: agonist-induced internalisation and down-regulation in intact cells.

Authors:  N Cook; S R Nahorski; D B Barnett
Journal:  Br J Pharmacol       Date:  1987-11       Impact factor: 8.739

8.  Effect of thyroid hormone on slow calcium channel function in cultured chick ventricular cells.

Authors:  D Kim; T W Smith; J D Marsh
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808

Review 9.  Involvement of tumor acidification in brain cancer pathophysiology.

Authors:  Avinash Honasoge; Harald Sontheimer
Journal:  Front Physiol       Date:  2013-11-01       Impact factor: 4.566
  9 in total

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