Literature DB >> 6137411

Relative potencies of the stereoisomers of bethanechol on muscarinic receptor.

C De Micheli, M De Amici, P Pratesi, E Grana, M G Santagostino Barbone.   

Abstract

The two enantiomers and the racemic form of bethanechol have been synthesized and their muscarinic activities evaluated on isolated rat jejunum. The stereoselectivity observed for bethanechol parallels that previously reported for acetyl-beta-methylcholine and muscarine on the same biological object.

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Year:  1983        PMID: 6137411

Source DB:  PubMed          Journal:  Farmaco Sci        ISSN: 0430-0920


  1 in total

1.  The effects of racemic bethanechol and its (R)- and (S)-enantiomers on pre- and postjunctional muscarine receptors in the guinea-pig ileum.

Authors:  H Schwörer; G Lambrecht; E Mutschler; H Kilbinger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-12       Impact factor: 3.000

  1 in total

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