Literature DB >> 6136896

A central role for the polyamines in the aetiology of schizophrenia.

R C Richardson-Andrews.   

Abstract

The general consensus of opinion in psychopharmacology is that the basic lesion in schizophrenia is a defect of the dopaminergic mechanism in some part or parts of the brain. In this article I wish to show that there is sufficient evidence to indicate that the central lesion involves the polyamines rather than dopamine.

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Year:  1983        PMID: 6136896     DOI: 10.1016/0306-9877(83)90059-2

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  4 in total

1.  The effects of some polyamines on putative behavioural indices of mesolimbic versus striatal dopaminergic function.

Authors:  S R Hirsch; R Richardson-Andrews; B Costall; M E Kelly; J de Belleroche; R J Naylor
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

Review 2.  Polyamines in mammalian pathophysiology.

Authors:  Francisca Sánchez-Jiménez; Miguel Ángel Medina; Lorena Villalobos-Rueda; José Luis Urdiales
Journal:  Cell Mol Life Sci       Date:  2019-06-21       Impact factor: 9.261

Review 3.  Implication of the polyamine system in mental disorders.

Authors:  Laura M Fiori; Gustavo Turecki
Journal:  J Psychiatry Neurosci       Date:  2008-03       Impact factor: 6.186

Review 4.  Polyamines and polyamine-metabolizing enzymes in schizophrenia: Current knowledge and concepts of therapy.

Authors:  Hans-Gert Bernstein; Gerburg Keilhoff; Gregor Laube; Henrik Dobrowolny; Johann Steiner
Journal:  World J Psychiatry       Date:  2021-12-19
  4 in total

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