Literature DB >> 6135875

Does virus persist in the uvea in multiple sclerosis, as in canine distemper encephalomyelitis?

B A Summers, H A Greisen, M J Appel.   

Abstract

Epidemiological studies suggest that multiple sclerosis (MS) might be triggered by an infectious agent. Uveitis has been observed in a small percentage of MS patients. Dogs with canine distemper encephalomyelitis, another demyelinating disease of the central nervous system, have an anterior uveitis which is usually mild and asymptomatic, and dogs with persistent CNS infection and chronic distemper encephalomyelitis harbour virus persistently in the uvea. These observations in dogs suggest that pathological and virological studies of the uveitis associated with MS would be worth while.

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Year:  1983        PMID: 6135875     DOI: 10.1016/s0140-6736(83)90346-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  3 in total

1.  Canine distemper virus clearance in chronic inflammatory demyelination.

Authors:  E Bollo; A Zurbriggen; M Vandevelde; R Fankhauser
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

2.  Macrophage Fc receptors control infectivity and neutralization of canine distemper virus-antibody complexes.

Authors:  M J Appel; S G Mendelson; W W Hall
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

Review 3.  Persistent viral infection. The carrier state.

Authors:  R C Povey
Journal:  Vet Clin North Am Small Anim Pract       Date:  1986-11       Impact factor: 2.093

  3 in total

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