Literature DB >> 6135608

Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.

M A Pereira, S L Herren, A L Britt.   

Abstract

Consistent with the proposed precursor relationship of GGTase-positive foci to hepatocarcinogenesis, the induction of foci by DBN was associated with the induction of hyperplastic nodules and hepatocellular carcinoma and the concurrent administration of sodium saccharin in the diet with DBN in the drinking water increased the tumorigenic response in the liver to DBN.

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Year:  1983        PMID： 6135608      PMCID： PMC1569209          DOI： 10.1289/ehp.8350169

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  17 in total

1.  Letter: Co-carcinogenic action of saccharin in the chemical induction of bladder cancer.

Authors:  R M Hicks; J S Wakefield; J Chowaniec
Journal:  Nature       Date:  1973-06-08       Impact factor: 49.962

2.  [Autoradiographic studies on RNA metabolism during dibutylnitrosamime-induced bladder tumors in rats].

Authors:  E Kunze; A Schauer; J Spielmann
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1971

3.  [Organotropic carcinogenic effects of 65 various N-nitroso- compounds on BD rats].

Authors:  H Druckrey; R Preussmann; S Ivankovic; D Schmähl
Journal:  Z Krebsforsch       Date:  1967

4.  [Enzyme-histochemical and autoradiographic studies on bladder papilloma induced by dibutyl nitrosamine in the rat].

Authors:  E Kunze; A Schauer
Journal:  Z Krebsforsch       Date:  1971

5.  [Induction of lungtumors and tumors of the urinary bladder in rats by di-n-butyl nitrosamine in dimethyl sulfoxide].

Authors:  J Sander; G Bürkle; V Bürkle
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1974

6.  Experimental studies on tumors of the urinary system of rats induced by chemical carcinogens.

Authors:  N Ito
Journal:  Acta Pathol Jpn       Date:  1973-02

7.  [Histochemistry of bladder papillomas induced by dibutylnitrosamine in the rat].

Authors:  E Kunze; A Schauer; R Calvoer
Journal:  Naturwissenschaften       Date:  1969-12

8.  Histochemical and ultrastructural demonstration of gamma-glutamyl transpeptidase activity.

Authors:  A M Rutenburg; H Kim; J W Fischbein; J S Hanker; H L Wasserkrug; A M Seligman
Journal:  J Histochem Cytochem       Date:  1969-08       Impact factor: 2.479

9.  Evaluation of a new model to detect bladder carcinogens or co-carcinogens; results obtained with saccharin, cyclamate and cyclophosphamide.

Authors:  R M Hicks; J Wakefield; J Chowaniec
Journal:  Chem Biol Interact       Date:  1975-09       Impact factor: 5.192

10.  Cocarcinogenic and tumor-promoting agents in tobacco carcinogenesis.

Authors:  B L Van Duuren; B M Goldschmidt
Journal:  J Natl Cancer Inst       Date:  1976-06       Impact factor: 13.506
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  1 in total

1.  Tumor promotion in rat liver.

Authors:  S L Herren; M A Pereira
Journal:  Environ Health Perspect       Date:  1983-04       Impact factor: 9.031
  1 in total

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