Literature DB >> 6133547

Absorption of beta-adrenoceptor antagonists to Amberlite resin.

A Heath, M Gabrielsson, C G Redgårdh.   

Abstract

The adsorption of beta-adrenoceptor blockers and the partial beta-adrenoceptor agonist prenalterol was studied in an in vitro haemoperfusion (HP) model. Metoprolol, alprenolol, propranolol and prenalterol adsorb well from the blood to the resin with extraction ratios nearing 1.0. Extraction ratio for practolol was 0.68 and for atenolol 0.49. Protein binding has little effect on the degree of adsorption, which is more dependent on water solubility.

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Year:  1983        PMID： 6133547      PMCID： PMC1427789          DOI： 10.1111/j.1365-2125.1983.tb01535.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  7 in total

1.  Pharmacokinetics of oral propranolol in chronic renal disease.

Authors:  D T Lowenthal; W A Briggs; T P Gibson; H Nelson; W J Cirksena
Journal:  Clin Pharmacol Ther       Date:  1974-11       Impact factor: 6.875

2.  The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat.

Authors:  G H Evans; A S Nies; D G Shand
Journal:  J Pharmacol Exp Ther       Date:  1973-07       Impact factor: 4.030

3.  Prenalterol as an antidote to massive doses of metoprolol--a cardiovascular study in the dog.

Authors:  T Andersson; A Heath; H Mattsson
Journal:  Acta Med Scand Suppl       Date:  1982

4.  Atenolol disposition in young and elderly subjects.

Authors:  P C Rubin; P J Scott; K McLean; A Pearson; D Ross; J L Reid
Journal:  Br J Clin Pharmacol       Date:  1982-02       Impact factor: 4.335

5.  Clinical pharmacologic observations on atenolol, a beta-adrenoceptor blocker.

Authors:  H C Brown; S G Carruthers; G D Johnston; J G Kelly; J McAinsh; D G McDevitt; R G Shanks
Journal:  Clin Pharmacol Ther       Date:  1976-11       Impact factor: 6.875

Review 6.  Clinical pharmacokinetics of beta-adrenoreceptor blocking drugs.

Authors:  G Johnsson; C G Regàrdh
Journal:  Clin Pharmacokinet       Date:  1976       Impact factor: 6.447

7.  Electron-capture-gas chromatographic determination of atenolol in plasma and urine, using a simplified procedure with improved selectivity.

Authors:  M Ervik; K Kylberg-Hanssen; P O Lagerström
Journal:  J Chromatogr       Date:  1980-06-13
  7 in total
  1 in total

1.  Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup.

Authors:  Josée Bouchard; Greene Shepherd; Robert S Hoffman; Sophie Gosselin; Darren M Roberts; Yi Li; Thomas D Nolin; Valéry Lavergne; Marc Ghannoum
Journal:  Crit Care       Date:  2021-06-10       Impact factor: 9.097
  1 in total

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