Literature DB >> 6132446

Vasoactive intestinal polypeptide and muscarinic receptors: supersensitivity induced by long-term atropine treatment.

B Hedlund, J Abens, T Bartfai.   

Abstract

Long-term treatment of rats with atropine induced large increases in the numbers of muscarinic receptors and receptors for vasoactive intestinal polypeptide in the salivary glands. Since receptors for vasoactive intestinal polypeptide coexist with muscarinic receptors on the same neurons in this preparation, the results suggest that a drug that alters the sensitivity of one receptor may also affect the sensitivity of the receptor for a costored transmitter and in this way contribute to the therapeutic or side effects of the drugs.

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Year:  1983        PMID： 6132446     DOI： 10.1126/science.6132446

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

Review 1.  Vasoactive intestinal peptide.

Authors:  S I Said
Journal:  J Endocrinol Invest       Date:  1986-04       Impact factor: 4.256

2.  BM-5, a centrally active partial muscarinic agonist with low tremorogenic activity. In vivo and in vitro studies.

Authors:  C Engström; A Undén; H Ladinsky; S Consolo; T Bartfai
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

3.  Effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus.

Authors:  I A Alonso; J C Prieto; E Arilla
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

4.  Syndromes of a complex lesion of greater and lesser superficial petrosal nerves (paradoxical facial hyperaemia, salivation, lacrimation and mucus excretion).

Authors:  S L Levin
Journal:  J Neurol       Date:  1987-01       Impact factor: 4.849

5.  Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide.

Authors:  I Gozes; A Bardea; A Reshef; R Zamostiano; S Zhukovsky; S Rubinraut; M Fridkin; D E Brenneman
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-09       Impact factor: 11.205

6.  The bimodal effect of cholinergic blocking agents on the human parotid gland deprived of parasympathetic control.

Authors:  S L Levin
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

7.  Development of Water-Compatible Molecularly Imprinted Polymers Based on Functionalized β-Cyclodextrin for Controlled Release of Atropine.

Authors:  Yahui He; Shaomei Zeng; A M Abd El-Aty; Ahmet Hacımüftüoğlu; Woldemariam Kalekristos Yohannes; Majid Khan; Yongxin She
Journal:  Polymers (Basel)       Date:  2020-01-06       Impact factor: 4.329
  7 in total

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