Literature DB >> 6132444

Irreversible ligands with high selectivity toward delta and mu opiate receptors.

K C Rice, A E Jacobson, T R Burke, B S Bajwa, R A Streaty, W A Klee.   

Abstract

Alkylating agents that display strong selectivity for opiate receptor types delta or mu were prepared by appropriate modification of the structures of the strong analgesics fentanyl, etonitazene, and endoethenotetrahydrooripavine. The availability of these substances should facilitate studies of the structural basis of receptor specificity and of the physiologic roles of these receptors.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6132444     DOI： 10.1126/science.6132444

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

Review 1.  Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications.

Authors:  Ruben S Vardanyan; Victor J Hruby
Journal:  Future Med Chem       Date:  2014-03       Impact factor: 3.808

2.  Computer-aided structure-affinity relationships in a set of piperazine and 3,8-diazabicyclo[3.2.1]octane derivatives binding to the mu-opioid receptor.

Authors:  D Barlocco; G Cignarella; G Greco; E Novellino
Journal:  J Comput Aided Mol Des       Date:  1993-10       Impact factor: 3.686

3.  Solid Phase Synthesis and Application of Labeled Peptide Derivatives: Probes of Receptor-Opioid Peptide Interactions.

Authors:  Jane V Aldrich; Vivek Kumar; Bhaswati Dattachowdhury; Angela M Peck; Xin Wang; Thomas F Murray
Journal:  Int J Pept Res Ther       Date:  2008-12-01       Impact factor: 1.931

4.  Opioid receptor antagonist affinity ligands: 6 beta-bromoacetamido-6-desoxynaltrexone and 6 beta-thioglycolamido-6-desoxynaltrexone.

Authors:  S Manda; N Lerner-Marmarosh; M Hashmi; L G Abood
Journal:  Neurochem Res       Date:  1992-12       Impact factor: 3.996

5.  Highly selective photoaffinity labeling of mu and delta opioid receptors.

Authors:  C Garbay-Jaureguiberry; A Robichon; V Daugé; P Rossignol; B P Roques
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

6.  Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking properties.

Authors:  Ki Duk Park; Xiao-Fang Yang; Hyosung Lee; Erik T Dustrude; Yuying Wang; Rajesh Khanna; Harold Kohn
Journal:  ACS Chem Neurosci       Date:  2013-01-16       Impact factor: 4.418

7.  Sodium dependent 3H-noradrenaline release from rat neocortical slices in the absence of extracellular calcium: presynaptic modulation by mu-opioid receptor and adenylate cyclase activation.

Authors:  A N Schoffelmeer; F Hogenboom; A H Mulder
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-11       Impact factor: 3.000

8.  Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.

Authors:  Ki Duk Park; Pierre Morieux; Christophe Salomé; Steven W Cotten; Onrapak Reamtong; Claire Eyers; Simon J Gaskell; James P Stables; Rihe Liu; Harold Kohn
Journal:  J Med Chem       Date:  2009-11-12       Impact factor: 7.446

9.  Non-xanthine heterocycles: activity as antagonists of A1- and A2-adenosine receptors.

Authors:  J W Daly; O Hong; W L Padgett; M T Shamim; K A Jacobson; D Ukena
Journal:  Biochem Pharmacol       Date:  1988-02-15       Impact factor: 5.858

10.  Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors.

Authors:  K A Jacobson; S Barone; U Kammula; G L Stiles
Journal:  J Med Chem       Date:  1989-05       Impact factor: 7.446
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.