Literature DB >> 6132382

Functional changes of intermediate filaments in fibroblastic cells revealed by a monoclonal antibody.

R Dulbecco, R Allen, S Okada, M Bowman.   

Abstract

We describe reversible changes of intermediate filaments of fibroblastic cells associated with changes in the functional state of the cells. The changes are revealed by comparing the immunofluorescence patterns given by a monoclonal antibody and a polyclonal serum, both recognizing vimentin. The state of the filaments depends on culture density; this effect cannot be attributed to the nutritional state of the cells, their growth rate, or substances released into the medium. It seems to depend mainly on the aggregation of filaments during strong cell movements. The possible significance of these findings for the functional role of intermediate filaments is discussed.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6132382      PMCID： PMC393721          DOI： 10.1073/pnas.80.7.1915

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

1.  Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates.

Authors:  W W Franke; E Schmid; S Winter; M Osborn; K Weber
Journal:  Exp Cell Res       Date:  1979-10-01       Impact factor: 3.905

2.  10 nm filaments in normal and transformed cells.

Authors:  R O Hynes; A T Destree
Journal:  Cell       Date:  1978-01       Impact factor: 41.582

3.  Production and characterization of cytotoxic Thy-1 antibody-secreting hybrid cell lines. Detection of T cell subsets.

Authors:  P Lake; E A Clark; M Khorshidi; G H Sunshine
Journal:  Eur J Immunol       Date:  1979-11       Impact factor: 5.532

4.  Structure of fibroblastic intermediate filaments: analysis of scanning transmission electron microscopy.

Authors:  A C Steven; J Wall; J Hainfeld; P M Steinert
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

5.  Lenticular intermediate-sized filaments: biosynthesis and interaction with plasma membrane.

Authors:  F C Ramaekers; I Dunia; H J Dodemont; E L Benedetti; H Bloemendal
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

6.  Intermediate filaments as mechanical integrators of cellular space.

Authors:  E Lazarides
Journal:  Nature       Date:  1980-01-17       Impact factor: 49.962

7.  Synemin: a new high molecular weight protein associated with desmin and vimentin filaments in muscle.

Authors:  B L Granger; E Lazarides
Journal:  Cell       Date:  1980-12       Impact factor: 41.582

8.  Phosphorylation of intermediate filament proteins by cAMP-dependent protein kinases.

Authors:  C M O'Connor; D L Gard; E Lazarides
Journal:  Cell       Date:  1981-01       Impact factor: 41.582

9.  Isolation and partial characterization of a cage of filaments that surrounds the mammalian mitotic spindle.

Authors:  G W Zieve; S R Heidemann; J R McIntosh
Journal:  J Cell Biol       Date:  1980-10       Impact factor: 10.539

10.  Nucleus-associated intermediate filaments from chicken erythrocytes.

Authors:  C L Woodcock
Journal:  J Cell Biol       Date:  1980-06       Impact factor: 10.539
View more
  15 in total

1.  Expression of vimentin by rabbit corneal epithelial cells during wound repair.

Authors:  N SundarRaj; J D Rizzo; S C Anderson; J P Gesiotto
Journal:  Cell Tissue Res       Date:  1992-02       Impact factor: 5.249

2.  Intermediate-filament expression in thyroid gland carcinomas.

Authors:  S Schröder; B Dockhorn-Dworniczak; H Kastendieck; W Böcker; W W Franke
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

3.  The monoclonal antibody 22/18 recognizes a conformational change in an intermediate filament of the newt, Notophthalmus viridescens, during limb regeneration.

Authors:  P Ferretti; J P Brockes
Journal:  Cell Tissue Res       Date:  1990-03       Impact factor: 5.249

4.  Identification of cells from fetal bladder epithelium in human amniotic fluid.

Authors:  H von Koskull; P Aula; L K Trejdosiewicz; I Virtanen
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  Differentiation patterns in two- and three-dimensional culture systems of human squamous carcinoma cell lines.

Authors:  R Knuechel; P Keng; F Hofstaedter; V Langmuir; R M Sutherland; D P Penney
Journal:  Am J Pathol       Date:  1990-09       Impact factor: 4.307

6.  Sequential changes of extracellular matrix and proliferation of Ito cells with enhanced expression of desmin and actin in focal hepatic injury.

Authors:  K Ogawa; J Suzuki; H Mukai; M Mori
Journal:  Am J Pathol       Date:  1986-12       Impact factor: 4.307

7.  Synthesis and secretion of alpha 2-macroglobulin by human glioma established cell lines.

Authors:  R Businaro; C Fabrizi; L Fumagalli; G M Lauro
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

8.  Contrary effect of lactic acid on expression of neuron-specific enolase and glial fibrillary acidic protein in human glioma cells.

Authors:  I Takeshita; H Sawa; T Nakamura; M Kuramitsu; K Kitamura; M Fukui
Journal:  Acta Neuropathol       Date:  1990       Impact factor: 17.088

9.  Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells.

Authors:  A Ben-Ze'ev
Journal:  J Cell Biol       Date:  1984-10       Impact factor: 10.539

10.  Assembly and exchange of intermediate filament proteins of neurons: neurofilaments are dynamic structures.

Authors:  K J Angelides; K E Smith; M Takeda
Journal:  J Cell Biol       Date:  1989-04       Impact factor: 10.539
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.