Literature DB >> 6130330

Epoprostenol (prostacyclin) and severe arterial disease. A double-blind trial.

J J Belch, A McKay, B McArdle, P Leiberman, J G Pollock, G D Lowe, C D Forbes, C R Prentice.   

Abstract

A 96 h infusion of epoprostenol (prostacyclin) or placebo was given as a treatment for rest pain to 28 patients with severe peripheral arterial disease. 24 h after the end of the infusion patients given epoprostenol had significantly less pain and took fewer analgesics tablets than did the controls. In some patients the epoprostenol effect lasted for over 1 month.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6130330     DOI: 10.1016/s0140-6736(83)91625-2

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  17 in total

1.  Iloprost and peripheral arterial disease in diabetic patients.

Authors:  A M Vicari; R Chiesa; G Mari; M Galimberti; V Di Carlo; G Pozza
Journal:  Acta Diabetol Lat       Date:  1991 Jan-Mar

2. 

Authors:  C Diehm; H Heidrich; F Spengel; K L Schulte; W Theiss
Journal:  Internist (Berl)       Date:  2000-11       Impact factor: 0.743

3.  Prolonged increase in digital blood flow following iloprost infusion in patients with systemic sclerosis.

Authors:  M Rademaker; R H Thomas; G Provost; J A Beacham; E D Cooke; J D Kirby
Journal:  Postgrad Med J       Date:  1987-08       Impact factor: 2.401

4.  Effects of taprostene, a stable prostacyclin analogue, on haemodynamics, platelet function and arachidonate metabolism in healthy volunteers.

Authors:  I Virgolini; P Fitscha; H Sinzinger; H Barth
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 5.  Nobel lecture, 8th December 1982. Adventures and excursions in bioassay: the stepping stones to prostacyclin.

Authors:  J R Vane
Journal:  Br J Pharmacol       Date:  1983-08       Impact factor: 8.739

Review 6.  Nobel lecture. Adventures and excursions in bioassay--the stepping stones to prostacyclin.

Authors:  J R Vane
Journal:  Postgrad Med J       Date:  1983-12       Impact factor: 2.401

Review 7.  Prostaglandins and the cardiovascular system.

Authors:  J R Vane
Journal:  Br Heart J       Date:  1983-05

8.  Alternative mechanisms for the hypotensive effects of adrenergic blockade.

Authors:  I A Greer; J J Walker; M McLaren; J J Belch; A A Calder; C D Forbes
Journal:  Br Med J (Clin Res Ed)       Date:  1983-11-19

Review 9.  Current issues in thrombosis prevention with antiplatelet drugs.

Authors:  G de Gaetano; C Cerletti; E Dejana; J Vermylen
Journal:  Drugs       Date:  1986-06       Impact factor: 9.546

10.  Circulation parameters during intravenous and intra-arterial administration of increasing doses of prostaglandin E1 in healthy subjects.

Authors:  T Brecht; M Ayaz
Journal:  Klin Wochenschr       Date:  1985-12-02
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.