| Literature DB >> 6128927 |
K Rickels, I Csanalosi, P Greisman, D Cohen, J Werblowsky, H A Ross, H Harris.
Abstract
The authors report the results of a large-scale double-blind study comparing the anxiolytic effects of alprazolam, a triazolobenzodiazepine; diazepam, a 1,4-benzodiazepine; and placebo in 151 anxious outpatients. Alprazolam and diazepam produced similar clinical improvement, which was significantly larger than improvement produced by placebo and was clearly evident after only 1 week of treatment. The incidence of sedation was lower with alprazolam than with diazepam.Entities:
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Year: 1983 PMID： 6128927 DOI： 10.1176/ajp.140.1.82
Source DB: PubMed Journal: Am J Psychiatry ISSN： 0002-953X Impact factor: 18.112