Literature DB >> 6127957

Serum levels of anticholinergic drugs and impaired recent memory in chronic schizophrenic patients.

L E Tune, M E Strauss, M F Lew, E Breitlinger, J T Coyle.   

Abstract

The authors tested working or recent memory in 24 stabilized schizophrenic outpatients who were taking psychotropic medication. Memory performance did not correlate with severity of schizophrenic symptoms, verbal IQ, or serum neuroleptic levels, but there was a significant inverse correlation between serum anticholinergic levels and performance on the memory task. The results suggest that therapeutic doses of anticholinergics may cause subtle impairments of cognitive functions.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6127957     DOI： 10.1176/ajp.139.11.1460

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  24 in total

1.  Cognitive effects of olanzapine treatment in schizophrenia.

Authors:  Susan R McGurk; M A Lee; K Jayathilake; Herbert Y Meltzer
Journal:  MedGenMed       Date:  2004-05-10

Review 2.  Delirium in hospitalized elderly.

Authors:  J Francis; W N Kapoor
Journal:  J Gen Intern Med       Date:  1990 Jan-Feb       Impact factor: 5.128

Review 3.  Delirium: an emerging frontier in the management of critically ill children.

Authors:  Heidi A B Smith; D Catherine Fuchs; Pratik P Pandharipande; Frederick E Barr; E Wesley Ely
Journal:  Crit Care Clin       Date:  2009-07       Impact factor: 3.598

4.  Anticholinergic serum levels and cognitive performance.

Authors:  O J Thienhaus; A Allen; J A Bennett; Y M Chopra; F P Zemlan
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1990       Impact factor: 5.270

5.  Higher anticholinergic drug scale (ADS) scores are associated with peripheral but not cognitive markers of cholinergic blockade. Cross sectional data from 21 Norwegian nursing homes.

Authors:  Hege Kersten; Espen Molden; Tiril Willumsen; Knut Engedal; Torgeir Bruun Wyller
Journal:  Br J Clin Pharmacol       Date:  2013-03       Impact factor: 4.335

Review 6.  Antipsychotic medications and the elderly: effects on cognition and implications for use.

Authors:  M J Byerly; M T Weber; D L Brooks; L R Snow; M A Worley; E Lescouflair
Journal:  Drugs Aging       Date:  2001       Impact factor: 3.923

Review 7.  Treating cognitive dysfunction in patients with schizophrenia.

Authors:  C A Galletly; C R Clark; A C MacFarlane
Journal:  J Psychiatry Neurosci       Date:  2000-03       Impact factor: 6.186

8.  Effects of two antidepressants on memory performance in depressed outpatients: a double-blind study.

Authors:  D L Lamping; B Spring; A J Gelenberg
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 9.  Verbal declarative memory dysfunction in schizophrenia: from clinical assessment to genetics and brain mechanisms.

Authors:  Michael A Cirillo; Larry J Seidman
Journal:  Neuropsychol Rev       Date:  2003-06       Impact factor: 7.444

10.  The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia.

Authors:  Sophia Vinogradov; Melissa Fisher; Heather Warm; Christine Holland; Margaret A Kirshner; Bruce G Pollock
Journal:  Am J Psychiatry       Date:  2009-07-01       Impact factor: 18.112
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.