Literature DB >> 6127729

Strategy for the discovery and development of a positive inotropic agent.

D B Evans, R E Weishaar, H R Kaplan.   

Abstract

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Year:  1982        PMID: 6127729     DOI: 10.1016/0163-7258(82)90005-5

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN: 0163-7258            Impact factor:   12.310


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  5 in total

Review 1.  Treatment of mild congestive heart failure. The potential for new drugs to reduce the risks.

Authors:  U Ravens; M Wehr
Journal:  Drug Saf       Date:  1991 Nov-Dec       Impact factor: 5.606

Review 2.  New mechanisms for positive inotropic agents: focus on the discovery and development of imazodan.

Authors:  R E Weishaar; D Kobylarz-Singer; B A Klinkefus
Journal:  Cardiovasc Drugs Ther       Date:  1989-03       Impact factor: 3.727

3.  UD-CG 115--a cardiotonic pyridazinone which elevates cyclic AMP and prolongs the action potential in guinea-pig papillary muscle.

Authors:  P Honerjäger; A Heiss; M Schäfer-Korting; G Schönsteiner; M Reiter
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-03       Impact factor: 3.000

4.  The cardiovascular pharmacology of ICI 170777 ((6RS)-6-methyl-5-(pyrid-4-yl)-3H,6H-1,3,4- thiadiazin-2-one) a novel compound with positive inotropic and vasodilator effects.

Authors:  M G Collis; J R Keddie; W Rouse
Journal:  Br J Pharmacol       Date:  1989-06       Impact factor: 8.739

5.  DPI 201-106, a novel cardioactive agent. Combination of cAMP-independent positive inotropic, negative chronotropic, action potential prolonging and coronary dilatory properties.

Authors:  G Scholtysik; R Salzmann; R Berthold; J W Herzig; U Quast; R Markstein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-05       Impact factor: 3.000

  5 in total

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