| Literature DB >> 6127542 |
F G McMahon, J R Ryan, K Akdamar, A Ertan.
Abstract
The effects of a new microencapsulated potassium chloride formulation on upper gastrointestinal tract mucosa was compared with that of a popular wax-matrix formulation in 48 healthy volunteers. After a week of KCl, subjects were gastroscoped, the endoscopist being blind to the type of preparation taken. Wax-matrix formulations were associated with a higher incidence of upper gastrointestinal lesions. The lesions were not accompanied by epigastric symptoms. Glycopyrrolate, given to some volunteers to decrease gastric emptying, aggravated the effects of potassium chloride.Entities:
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Year: 1982 PMID： 6127542 DOI： 10.1016/s0140-6736(82)90002-2
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321