Literature DB >> 6127085

Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193).

H N Jayaram, R L Dion, R I Glazer, D G Johns, R K Robins, P C Srivastava, D A Cooney.   

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Year:  1982        PMID: 6127085     DOI: 10.1016/0006-2952(82)90532-9

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  19 in total

1.  Induction of erythroid differentiation and modulation of gene expression by tiazofurin in K-562 leukemia cells.

Authors:  E Olah; Y Natsumeda; T Ikegami; Z Kote; M Horanyi; J Szelenyi; E Paulik; T Kremmer; S R Hollan; J Sugar
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

2.  Phase I and pharmacokinetic study of tiazofurin (NSC 286193) administered by 5-day continuous infusion.

Authors:  D Raghavan; J Bishop; D Sampson; J Grygiel; R Woods; A Coates; R Fox
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

3.  Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.

Authors:  T D Colby; K Vanderveen; M D Strickler; G D Markham; B M Goldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

Review 4.  Tiazofurin: a new antitumor agent.

Authors:  P J O'Dwyer; D D Shoemaker; H N Jayaram; D G Johns; D A Cooney; S Marsoni; L Malspeis; J Plowman; J P Davignon; R D Davis
Journal:  Invest New Drugs       Date:  1984       Impact factor: 3.850

5.  Guanine ribonucleotide depletion in mammalian cells. A target of purine antimetabolites.

Authors:  B T Nguyen; M B Cohen; W Sadée
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333

6.  Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent.

Authors:  J J Kirsi; J A North; P A McKernan; B K Murray; P G Canonico; J W Huggins; P C Srivastava; R K Robins
Journal:  Antimicrob Agents Chemother       Date:  1983-09       Impact factor: 5.191

Review 7.  Mechanism targeted discovery of antitumor marine natural products.

Authors:  Dale G Nagle; Yu-Dong Zhou; Flor D Mora; Kaleem A Mohammed; Yong-Pil Kim
Journal:  Curr Med Chem       Date:  2004-07       Impact factor: 4.530

8.  Studies of purine and tiazofurin metabolism in drug sensitive human chronic myelogenous leukemia K 562 cells.

Authors:  K Pillwein; H N Jayaram; G Weber
Journal:  Blut       Date:  1988-08

9.  Schedule-dependent synergistic action of tiazofurin and dipyridamole on hepatoma 3924A cells.

Authors:  H N Jayaram; K Murayama; K Pillwein; W Zhen; G Weber
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

10.  Clinical pharmacology of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).

Authors:  R M Green; D J Stewart; J A Maroun
Journal:  Invest New Drugs       Date:  1986       Impact factor: 3.850

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