Literature DB >> 6126829

The nuclear localization of a putative neurotransmitter receptor.

S C Bondy, K R Cameron, A K Agrawal.   

Abstract

A high affinity strychnine binding site has been identified within a membrane fraction prepared from partially purified rat brain nuclei. This interaction appears similar in its characteristics to that occurring in the non-nuclear membrane fraction which is thought to occur at the synaptic glycine receptor complex. Both the nuclear and non-nuclear membrane binding of tritiated strychnine is greater within the pons-medulla region than in the cerebral cortex. Nuclear membrane binding sites for dopamine, norepinephrine (beta-adrenergic), acetylcholine (muscarinic), GABA, and diazepam were not detected.

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Year:  1982        PMID： 6126829     DOI： 10.1007/bf00965053

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  18 in total

1.  Intracellular polypeptide hormone receptors. Characterization and induction of lactogen receptors in the Golgi apparatus of rat liver.

Authors:  B I Posner; Z Josefsberg; J J Bergerson
Journal:  J Biol Chem       Date:  1979-12-25       Impact factor: 5.157

2.  Localization of acetylcholine receptors during synaptogenesis in retina.

Authors:  Z Vogel; M Nirenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

3.  Internalisation of gonadotrophin--receptor complex in ovarian luteal cells.

Authors:  P M Conn; M Conti; J P Harwood; M L Dufau; K J Catt
Journal:  Nature       Date:  1978-08-10       Impact factor: 49.962

4.  Direct binding studies of 125 I-alpha-bungarotoxin and 3H-quinuclidinyl benzilate interaction with axon plasma membrane fragments. Evidence for nicotinic and muscarinic binding sites.

Authors:  J K Marquis; D C Hilt; H G Mautner
Journal:  Biochem Biophys Res Commun       Date:  1977-09-23       Impact factor: 3.575

5.  The relationship between DNA synthesis and the synthesis of nuclear proteins in rat brain during development.

Authors:  J A Burdman
Journal:  J Neurochem       Date:  1972-06       Impact factor: 5.372

6.  beta-Adrenergic receptors from frog erythrocytes: receptor internalization as a mechanism for receptor desensitization.

Authors:  D M Chuang; L Farber; W J Kinnier; E Costa
Journal:  Adv Biochem Psychopharmacol       Date:  1980

7.  Substrate specificity of [3H]muscimol binding to a particulate fraction of a neuron-enriched culture of embryonic rat brain.

Authors:  F V DeFeudis; L Ossola; G Schmitt; P Mandel
Journal:  J Neurochem       Date:  1980-04       Impact factor: 5.372

8.  Binding of muscimol and GABA in sub-fractions of a crude membrane fraction of rat brain.

Authors:  V Varga; F V DeFeudis; L Ossola; M Geffard; P Mandel
Journal:  Biochem Pharmacol       Date:  1980-04-01       Impact factor: 5.858

9.  Strychnine binding associated with glycine receptors of the central nervous system.

Authors:  A B Young; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

10.  Diazepam receptor: specific nuclear binding of [3H]flunitrazepam.

Authors:  H B Bosmann; D P Penney; K R Case; K Averill
Journal:  Proc Natl Acad Sci U S A       Date:  1980-02       Impact factor: 11.205
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